Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | APAF1 | O14727 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26422895 | 0.83 | HDAC4 (0.46) | MAPTSMN1; SMN2KDM4EALDH1A1APAF1 | |
| SCHEMBL22925831 | 0.81 | HDAC4 (0.49) | MAPTSMN1; SMN2KDM4EALDH1A1APAF1 | |
| SCHEMBL29620876 | 0.81 | HDAC4 (0.49) | MAPTSMN1; SMN2KDM4EALDH1A1APAF1 | |
| SCHEMBL22925947 | 0.81 | HDAC4 (0.49) | MAPTSMN1; SMN2KDM4EALDH1A1APAF1 | |
| SCHEMBL29620920 | 0.81 | HDAC4 (0.49) | MAPTSMN1; SMN2KDM4EALDH1A1APAF1 | |
| SCHEMBL12498160 | 0.81 | HDAC4 (0.46) | MAPTSMN1; SMN2KDM4EALDH1A1APAF1 | |
| SCHEMBL16547509 | 0.79 | ALDH1A1 (0.44) | MAPTSMN1; SMN2KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL27133083 | 0.78 | ADRB1 (0.46) | MAPTKDM4EALDH1A1MEN1CYP1A2 | |
| SCHEMBL27496862 | 0.78 | NOTUM (0.44) | MAPTSMN1; SMN2KDM4EALDH1A1TDP1 | |
| SCHEMBL27915290 | 0.77 | EGLN1 (0.55) | HDAC4MEN1CYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023128786-A1 | NEW ANTIVIRAL TRIAZOLE DERIVATIVES, THEIR SYNTHESIS AND THEIR USE FOR TREATMENT OF MAMMALIAN VIRAL INFECTIONS | COLLABORATIONS PHARMACEUTICALS, INC (US) | 2023-07-06 | — | — | WO | disclosed |
| US-20220274970-A1 | INHIBITOR COMPOUNDS | Cincera Therapeutics Pty Ltd (AU) | 2022-09-01 | — | — | US | disclosed |
| EP-3008045-B1 | ANTIBACTERIAL THIAZOLECARBOXYLIC ACIDS | ANTABIO SAS (FR) | 2018-05-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220274970-A1 | INHIBITOR COMPOUNDS | SERPINB1, MMP1, SSB | MAPT 2083/4885SMN1; SMN2 863/4885KDM4E 1551/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.