Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 3/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.42 |
| ▸ | IL6 | P05231 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20804977 | 0.86 | FFAR1 (0.46) | FFAR1FFAR4ALOX15KDM4ECYP1A2 | |
| SCHEMBL1158620 | 0.82 | ADRB2 (0.54) | CYP1A2ACHEADRB2LMNA | |
| SCHEMBL25974313 | 0.82 | FFAR1 (0.46) | FFAR1FFAR4ALOX15KDM4ECYP1A2 | |
| SCHEMBL773187 | 0.82 | ALOX15 (0.68) | FFAR1FFAR4ALOX15KDM4ECYP1A2 | |
| SCHEMBL14300877 | 0.81 | FFAR1 (0.46) | FFAR1FFAR4LMNACYP2C19ALDH1A1 | |
| SCHEMBL3629149 | 0.78 | KDM4E (0.68) | ALOX15KDM4ECYP1A2ADRB2ADRB1 | |
| SCHEMBL25974447 | 0.77 | LMNA (0.39) | LMNACYP2C19 | |
| SCHEMBL23047176 | 0.77 | CYP2C19 (0.44) | KDM4ECYP1A2ADRB2ADRB1ADRB3 | |
| SCHEMBL29559341 | 0.77 | FFAR1 (0.42) | FFAR1FFAR4ALOX15KDM4ECYP1A2 | |
| SCHEMBL6832641 | 0.76 | FFAR1 (0.49) | FFAR1FFAR4KDM4ECYP1A2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970275-B1 | PROTEIN KINASE C INHIBITORS AND USES THEREOF | RIGEL PHARMACEUTICALS INC (US) | 2018-05-09 | — | — | EP | disclosed |