SCHEMBL20124968

SCHEMBL20124968

CCCCOC(=O)N1CCCCC1C(=O)OCC

nearest known ligand 0.55

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
FKBP1A P62942 16/20 0.55
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
RAB9A P51151 1/20 0.42
ALDH1A1 P00352 2/20 0.41
KDM4E B2RXH2 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL695607 0.90 FKBP1A (0.51) FKBP1ARAB9A
SCHEMBL24661351 0.90 FKBP1A (0.65) FKBP1AMEN1KMT2ARAB9AALDH1A1
SCHEMBL13374841 0.89 FKBP1A (0.53) FKBP1ARAB9A
SCHEMBL3710312 0.86 RAB9A (0.57) FKBP1ARAB9AALDH1A1
SCHEMBL7815566 0.86 RAB9A (0.57) FKBP1ARAB9AALDH1A1
SCHEMBL7811720 0.86 RAB9A (0.57) FKBP1ARAB9AALDH1A1
SCHEMBL3656325 0.84 FKBP1A (0.48) FKBP1ARAB9A
SCHEMBL5727740 0.84 FKBP1A (0.48) FKBP1ARAB9A
SCHEMBL8141816 0.84 FKBP1A (0.48) FKBP1ARAB9A
SCHEMBL4748921 0.84 LMNA (0.46) FKBP1ARAB9AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1866347-B1 PROPYLENE POLYMER CATALYST DONOR COMPONENT INEOS TECH USA LLC (US) 2018-05-09 EP disclosed