Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 17/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8141816 | 0.91 | FKBP1A (0.48) | FKBP1ARAB9AL3MBTL1LMNAPOLB | |
| SCHEMBL3656325 | 0.91 | FKBP1A (0.48) | FKBP1ARAB9AL3MBTL1LMNAPOLB | |
| SCHEMBL5727740 | 0.91 | FKBP1A (0.48) | FKBP1ARAB9AL3MBTL1LMNAPOLB | |
| SCHEMBL4748921 | 0.91 | LMNA (0.46) | FKBP1ARAB9ALMNAPOLBSMN1; SMN2 | |
| SCHEMBL20124968 | 0.90 | FKBP1A (0.55) | FKBP1ARAB9A | |
| SCHEMBL3712964 | 0.88 | FKBP1A (0.51) | FKBP1AL3MBTL1 | |
| SCHEMBL7261287 | 0.88 | FKBP1A (0.51) | FKBP1AL3MBTL1 | |
| SCHEMBL2634067 | 0.88 | RAB9A (0.62) | RAB9AL3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL695608 | 0.88 | RAB9A (0.62) | RAB9AL3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL5493674 | 0.88 | RAB9A (0.62) | RAB9AL3MBTL1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2640719-A2 | ANTIVIRAL COMPOUNDS | Gilead Sciences, Inc. (US) | 2013-09-25 | — | — | EP | disclosed |
| WO-2012068234-A2 | ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2012-05-24 | — | — | WO | disclosed |
| EP-2421855-A1 | DIARYL ETHERS | Tibotec Pharmaceuticals (IE) | 2012-02-29 | — | — | EP | disclosed |
| WO-2010122162-A1 | DIARYL ETHERS | TIBOTEC PHARMACEUTICALS (IE) | 2010-10-28 | — | — | WO | disclosed |
| EP-2242752-A1 | IMIDAZOLYL BIPHENYL IMIDAZOLES AS HEPATITIS C VIRUS INHIBITORS | Bristol-Myers Squibb Company (US) | 2010-10-27 | — | — | EP | disclosed |
| WO-2009102325-A1 | IMIDAZOLYL BIPHENYL IMIDAZOLES AS HEPATITIS C VIRUS INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2009-08-20 | — | — | WO | disclosed |