Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20125119 | 1.00 | DRD2 (0.35) | DRD2DRD1CHRNB2CHRNA4PDK2 | |
| SCHEMBL24344900 | 0.84 | CHRNB2 (0.35) | DRD2DRD1CHRNB2CHRNA4PDK2 | |
| SCHEMBL24344837 | 0.79 | HTR2A (0.33) | CHRNB2CHRNA4 | |
| SCHEMBL18560180 | 0.68 | KIF11 (0.40) | DRD2DRD1CHRNB2CHRNA4 | |
| SCHEMBL25786311 | 0.68 | CHRNB2 (0.31) | CHRNB2CHRNA4 | |
| SCHEMBL23938075 | 0.68 | CHRNB2 (0.31) | CHRNB2CHRNA4 | |
| SCHEMBL13199592 | 0.64 | CA1 (0.36) | DRD2DRD1CHRNB2CHRNA4PDK2 | |
| SCHEMBL7914307 | 0.64 | CA1 (0.36) | DRD2DRD1CHRNB2CHRNA4PDK2 | |
| SCHEMBL25786312 | 0.63 | HTR2A (0.33) | CHRNB2CHRNA4 | |
| SCHEMBL23416751 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3318557-A2 | QUINOLONE COMPOUND | Otsuka Pharmaceutical Co., Ltd. (JP) | 2018-05-09 | — | — | EP | disclosed |