Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 4/20 | 0.54 |
| ▸ | NOS2 | P35228 | 4/20 | 0.54 |
| ▸ | NOS1 | P29475 | 3/20 | 0.54 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.39 |
| ▸ | CCR1 | P32246 | 1/20 | 0.34 |
| ▸ | CCR5 | P51681 | 1/20 | 0.34 |
| ▸ | CCR8 | P51685 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | IKBKB | O14920 | 1/20 | 0.30 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25129348 | 0.81 | NOS3 (0.47) | NOS3NOS2NOS1CYP2A6CCR1 | |
| SCHEMBL20124974 | 0.79 | NOS3 (0.54) | NOS3NOS2NOS1CYP2A6CCR1 | |
| SCHEMBL8296665 | 0.79 | NOS3 (0.54) | NOS3NOS2NOS1CYP2A6CCR1 | |
| SCHEMBL11881227 | 0.78 | CCR1 (0.37) | NOS3NOS2NOS1CCR1CCR5 | |
| SCHEMBL22802074 | 0.77 | PARP1 (0.36) | NOS3NOS2NOS1KMT2AHTT | |
| SCHEMBL29634226 | 0.77 | PARP1 (0.36) | NOS3NOS2NOS1KMT2AHTT | |
| SCHEMBL19622314 | 0.77 | PDXK (0.37) | NOS3NOS2NOS1CCR1CCR5 | |
| SCHEMBL8341853 | 0.76 | NOS3 (0.50) | NOS3NOS2NOS1CYP2A6CCR1 | |
| SCHEMBL2123346 | 0.75 | MAP4K4 (0.31) | NOS3NOS2NOS1KMT2AHTT | |
| SCHEMBL12829260 | 0.75 | USP7 (0.35) | NOS3NOS2NOS1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025106949-A1 | WRN INHIBITORS | RADD PHARMACEUTICALS, INC. (US) | 2025-05-22 | — | — | WO | disclosed |
| WO-2019014300-A1 | PHENYLACETAMIDES AS INHIBITORS OF ROCK | BRISTOL-MYERS SQUIBB COMPANY (US) | 2019-01-17 | — | — | WO | disclosed |
| EP-3318557-A2 | QUINOLONE COMPOUND | Otsuka Pharmaceutical Co., Ltd. (JP) | 2018-05-09 | — | — | EP | disclosed |