SCHEMBL29634226

SCHEMBL29634226

C=Cc1cnc(N)c(C=C)c1

nearest known ligand 0.36

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 1/20 0.36
HTT P42858 1/20 0.31
KMT2A Q03164 1/20 0.31
NOS3 P29474 1/20 0.31
NOS1 P29475 1/20 0.31
NOS2 P35228 1/20 0.31
ALDH1A1 P00352 1/20 0.31
TP53 P04637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22802074 1.00 PARP1 (0.36) PARP1HTTKMT2ANOS3NOS1
SCHEMBL3275270 0.80 PARP1 (0.37) PARP1HTTKMT2ANOS3NOS1
SCHEMBL12829260 0.77 USP7 (0.35) HTTKMT2ANOS3NOS1NOS2
SCHEMBL20125043 0.77 NOS3 (0.54) HTTKMT2ANOS3NOS1NOS2
SCHEMBL18801007 0.77 ATR (0.31) HTTKMT2ANOS3NOS1NOS2
SCHEMBL2123346 0.77 MAP4K4 (0.31) HTTKMT2ANOS3NOS1NOS2
SCHEMBL22864248 0.77 CPB2 (0.36) PARP1HTTKMT2ANOS3NOS1
SCHEMBL19792099 0.76 NOS3 (0.36) PARP1NOS3NOS1NOS2
SCHEMBL9797914 0.74 PDXK (0.38) PARP1ALDH1A1TP53
SCHEMBL18801076 0.74 TSHR (0.37) KMT2AALDH1A1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114573750-B Alkaline functionalized porous polyion liquid material and preparation method and application thereof 浙江大学杭州国际科创中心 2023-05-02 CN claimed
CN-114573750-A Alkaline functionalized porous polyion liquid material as well as preparation method and application thereof 浙江大学杭州国际科创中心 2022-06-03 CN claimed
CN-114573750-B Alkaline functionalized porous polyion liquid material and preparation method and application thereof 浙江大学杭州国际科创中心 2023-05-02 CN disclosed
CN-114573750-A Alkaline functionalized porous polyion liquid material as well as preparation method and application thereof 浙江大学杭州国际科创中心 2022-06-03 CN disclosed