Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 1/20 | 0.30 |
| ▸ | KIT | P10721 | 1/20 | 0.30 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.30 |
| ▸ | CDK11B | P21127 | 1/20 | 0.30 |
| ▸ | FLT3 | P36888 | 1/20 | 0.30 |
| ▸ | CDKL2 | Q92772 | 1/20 | 0.30 |
| ▸ | CHKA | P35790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12336296 | 0.89 | CHKA (0.35) | PDGFRBKITPDGFRACDK11BFLT3 | |
| SCHEMBL12336247 | 0.86 | PDGFRB (0.35) | PDGFRBKITPDGFRACDK11BFLT3 | |
| SCHEMBL14949266 | 0.83 | PDGFRB (0.40) | PDGFRBKITPDGFRACDK11BFLT3 | |
| SCHEMBL14949693 | 0.82 | PDGFRB (0.35) | PDGFRBKITPDGFRACDK11BFLT3 | |
| SCHEMBL12336255 | 0.82 | PDGFRB (0.33) | PDGFRBKITPDGFRACDK11BFLT3 | |
| SCHEMBL14949291 | 0.78 | KIT (0.38) | PDGFRBKITPDGFRACDK11BFLT3 | |
| SCHEMBL12336257 | 0.78 | PDGFRB (0.39) | PDGFRBKITPDGFRACDK11BFLT3 | |
| SCHEMBL14949254 | 0.77 | RAB9A (0.38) | CHKA | |
| SCHEMBL20125542 | 0.77 | PDGFRB (0.31) | PDGFRBKITPDGFRACDK11BFLT3 | |
| SCHEMBL12348779 | 0.77 | NUDT1 (0.37) | PDGFRBKITPDGFRACDK11BFLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2550266-B1 | HETEROCYCLIC COMPOUNDS USEFUL FOR KINASE INHIBITION | AMITECH THERAPEUTICS SOLUTIONS INC (US) | 2018-05-09 | — | — | EP | disclosed |