Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | ADH1B | P00325 | 2/20 | 0.32 |
| ▸ | ADH1C | P00326 | 2/20 | 0.32 |
| ▸ | ADH1A | P07327 | 2/20 | 0.32 |
| ▸ | ADH4 | P08319 | 2/20 | 0.32 |
| ▸ | ADH7 | P40394 | 2/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
| ▸ | CTSB | P07858 | 1/20 | 0.32 |
| ▸ | GMNN | O75496 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | LAP3 | P28838 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21067332 | 0.84 | TSHR (0.31) | TSHRSMN1; SMN2 | |
| SCHEMBL20125698 | 0.82 | CYP3A4 (0.31) | TSHRGMNNMAPTSMN1; SMN2 | |
| SCHEMBL7372332 | 0.81 | CA2 (0.41) | EPHX1CA2TSHRCES2CTSL | |
| SCHEMBL22679726 | 0.77 | EPHX1 (0.34) | EPHX1CA2TSHRADH1BADH1C | |
| SCHEMBL5137869 | 0.77 | CYP3A4 (0.32) | TSHRGMNNMAPTSMN1; SMN2 | |
| SCHEMBL22757647 | 0.75 | SPHK1 (0.41) | EPHX1CA2TSHRCES2GMNN | |
| SCHEMBL30572188 | 0.73 | GRIK1 (0.49) | EPHX1GMNNTP53POLBMAPT | |
| SCHEMBL26391603 | 0.73 | GRIK1 (0.49) | EPHX1GMNNTP53POLBMAPT | |
| SCHEMBL20634256 | 0.72 | TSHR (0.57) | CA2TSHRCES2CTSLCTSB | |
| SCHEMBL867481 | 0.72 | TSHR (0.57) | CA2TSHRCES2CTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180127586-A1 | DIHYDROPYRENE DERIVATIVES, PROCESSES FOR PREPARING THE SAME AND THEIR USES | UNIVERSITE GRENOBLE ALPES (FR) | 2018-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180127586-A1 | DIHYDROPYRENE DERIVATIVES, PROCESSES FOR PREPARING THE SAME AND THEIR USES | DHPS, DPYD, DHODH | EPHX1 666/4885CA2 4362/4885TSHR 4819/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.