Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | THPO | P40225 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | GMNN | O75496 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20125696 | 0.82 | EPHX1 (0.37) | TSHRGMNNMAPTSMN1; SMN2 | |
| SCHEMBL25247617 | 0.77 | LMNA (0.40) | LMNAHIF1AEPAS1 | |
| SCHEMBL6130047 | 0.77 | LMNA (0.48) | LMNA | |
| SCHEMBL23128780 | 0.75 | LMNA (0.42) | TSHRLMNASMN1; SMN2HIF1AEPAS1 | |
| SCHEMBL20126769 | 0.75 | NOS2 (0.35) | CYP3A4CYP2D6TSHRNFKB1THPO | |
| SCHEMBL17449732 | 0.74 | CYP3A4 (0.32) | CYP3A4CYP2D6TSHRNFKB1THPO | |
| SCHEMBL5137869 | 0.74 | CYP3A4 (0.32) | CYP3A4CYP2D6TSHRNFKB1THPO | |
| SCHEMBL12851469 | 0.74 | CYP3A4 (0.32) | CYP3A4CYP2D6TSHRNFKB1THPO | |
| SCHEMBL21067332 | 0.74 | TSHR (0.31) | TSHRSMN1; SMN2 | |
| SCHEMBL20126725 | 0.71 | SIGMAR1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3303344-B1 | DIHYDROPYRENE DERIVATIVES, PROCESSES FOR PREPARING THE SAME AND THEIR USES | UNIV GRENOBLE ALPES (FR) | 2020-09-30 | — | — | EP | disclosed |
| US-20180127586-A1 | DIHYDROPYRENE DERIVATIVES, PROCESSES FOR PREPARING THE SAME AND THEIR USES | UNIVERSITE GRENOBLE ALPES (FR) | 2018-05-10 | — | — | US | disclosed |
| US-20180127586-A1 | DIHYDROPYRENE DERIVATIVES, PROCESSES FOR PREPARING THE SAME AND THEIR USES | UNIVERSITE GRENOBLE ALPES (FR) | 2018-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180127586-A1 | DIHYDROPYRENE DERIVATIVES, PROCESSES FOR PREPARING THE SAME AND THEIR USES | DHPS, DPYD, DHODH | CYP3A4 29/4885CYP2D6 26/4885TSHR 4819/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.