SCHEMBL21067332

SCHEMBL21067332

CCCSSC[C@@H](N)C=O

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20125696 0.84 EPHX1 (0.37) TSHRSMN1; SMN2
SCHEMBL5137869 0.83 CYP3A4 (0.32) TSHRSMN1; SMN2
SCHEMBL12851469 0.83 CYP3A4 (0.32) TSHRSMN1; SMN2
SCHEMBL17449732 0.83 CYP3A4 (0.32) TSHRSMN1; SMN2
SCHEMBL8024973 0.80
SCHEMBL20125698 0.74 CYP3A4 (0.31) TSHRSMN1; SMN2
SCHEMBL20648570 0.74 TSHR (0.32) TSHR
SCHEMBL12773076 0.72
SCHEMBL10331496 0.71 TRPA1 (0.50) SMN1; SMN2
SCHEMBL24295875 0.71 NOS2 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11446398-B2 Regulated biocircuit systems OBSIDIAN THERAPEUTICS, INC. (US) 2022-09-20 US disclosed
US-20190192691-A1 REGULATED BIOCIRCUIT SYSTEMS OBSIDIAN THERAPEUTICS, INC. 2019-06-27 US disclosed