Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TLR2 | O60603 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20160384 | 0.93 | ALDH1A1 (0.34) | ALDH1A1TSHRHPGDKDM4ESMN1; SMN2 | |
| SCHEMBL16948553 | 0.83 | SMN1; SMN2 (0.47) | ALDH1A1TSHRHPGDKDM4ESMN1; SMN2 | |
| SCHEMBL10036615 | 0.81 | LMNA (0.48) | ALDH1A1TSHRKMT2A | |
| SCHEMBL16944222 | 0.79 | TSHR (0.37) | ALDH1A1TSHRHPGDKDM4ESMN1; SMN2 | |
| SCHEMBL25892891 | 0.75 | TSHR (0.46) | ALDH1A1TSHRHPGDKDM4ESMN1; SMN2 | |
| SCHEMBL23729617 | 0.74 | TSHR (0.45) | ALDH1A1TSHRHPGDSMN1; SMN2KMT2A | |
| SCHEMBL26700900 | 0.74 | HPGD (0.43) | ALDH1A1TSHRHPGDSMN1; SMN2KMT2A | |
| SCHEMBL26708616 | 0.73 | TSHR (0.44) | ALDH1A1TSHRHPGDSMN1; SMN2KMT2A | |
| SCHEMBL23729791 | 0.73 | TSHR (0.44) | TSHRHPGDSMN1; SMN2KMT2ATLR2 | |
| SCHEMBL19333173 | 0.72 | SMN1; SMN2 (0.39) | ALDH1A1TSHRHPGDKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180134843-A1 | AQUEOUS POLYGLYCIDOL SYNTHESIS WITH ULTRA-LOW BRANCHING | VANDERBILT UNIVERSITY | 2018-05-17 | — | — | US | disclosed |
| US-20180125983-A1 | Linear Polyester and Semi-Linear Glycidol Polymer Systems: Formulation and Synthesis of Novel Monomers and Macromolecular Structures | UNIV VANDERBILT (US) | 2018-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180125983-A1 | Linear Polyester and Semi-Linear Glycidol Polymer Systems: Formulation and Synthesis of Novel Monomers and Macromolecular Structures | STT3A, STT3B, B3GAT3 | ALDH1A1 4091/4885TSHR 2588/4885HPGD 1749/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.