SCHEMBL20127463

SCHEMBL20127463

c1cc(-c2c3ccccc3c(-c3c4ccccc4cc4c3oc3ccccc34)c3ccccc23)cc(-c2cccc3c2oc2ccccc23)c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 3/20 0.51
GGPS1 O95749 1/20 0.44
PTGES2 Q9H7Z7 1/20 0.41
PRKDC P78527 8/20 0.39
PRMT5 O14744 1/20 0.36
WDR77 Q9BQA1 1/20 0.36
AHR P35869 1/20 0.35
PIK3CD O00329 2/20 0.35
PIK3CB P42338 1/20 0.35
ATM Q13315 1/20 0.34
XRCC6 P12956 1/20 0.33
XRCC5 P13010 1/20 0.33
PIK3CA P42336 1/20 0.33
PLA2G2A P14555 1/20 0.32
PLA2G4A P47712 1/20 0.32
KDM4E B2RXH2 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
GPR84 Q9NQS5 1/20 0.32
CES1 P23141 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10122556 0.92 ALOX5 (0.42) ALOX5GGPS1PTGES2PRKDCAHR
SCHEMBL20127458 0.91 ALOX5 (0.52) ALOX5GGPS1PTGES2PRKDCPRMT5
SCHEMBL20127459 0.90 ALOX5 (0.39) ALOX5GGPS1PTGES2PRKDCAHR
SCHEMBL20127666 0.89 ALOX5 (0.56) ALOX5GGPS1PTGES2PRKDCPRMT5
SCHEMBL10122589 0.88 ALOX5 (0.43) ALOX5GGPS1PTGES2PRKDCAHR
SCHEMBL10122558 0.88 PLA2G2A (0.40) ALOX5PRKDCAHRPIK3CDXRCC6
SCHEMBL20127457 0.88 ALOX5 (0.48) ALOX5GGPS1PTGES2PRKDCAHR
SCHEMBL10122695 0.88 AHR (0.41) ALOX5GGPS1PRKDCAHRPIK3CD
SCHEMBL125790 0.88 ALOX5 (0.63) ALOX5GGPS1PTGES2PRKDCPRMT5
SCHEMBL15195392 0.87 ALOX5 (0.53) ALOX5GGPS1PTGES2PRKDCPRMT5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180208836-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2018-07-26 US disclosed
US-20180208836-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2018-07-26 US disclosed
US-20180130968-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2018-05-10 US disclosed
US-20180130968-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2018-05-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180130968-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE RER1, NR0B1, NR2E1 ALOX5 4115/4885GGPS1 4058/4885PTGES2 4331/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.