SCHEMBL20127601

SCHEMBL20127601

c1ccc2c(c1)oc1c2ccc2c3cc(-c4c5ccccc5c(-c5ccc6c7ccccc7c7ccccc7c6c5)c5ccccc45)ccc3oc21

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.44
MAPT P10636 3/20 0.43
NPC1 O15118 3/20 0.43
KMT2A Q03164 3/20 0.43
SMN1; SMN2 Q16637 3/20 0.43
KDM4E B2RXH2 2/20 0.43
MEN1 O00255 2/20 0.43
ALDH1A1 P00352 2/20 0.43
HPGD P15428 2/20 0.43
RAB9A P51151 2/20 0.43
AHR P35869 4/20 0.40
PLA2G2A P14555 3/20 0.38
PLA2G4A P47712 3/20 0.38
PGR P06401 1/20 0.38
DYRK1A Q13627 1/20 0.37
CYP1A2 P05177 1/20 0.36
CYP2D6 P10635 1/20 0.36
CYP2C19 P33261 1/20 0.36
MAOB P27338 1/20 0.36
PLA2G10 O15496 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10122688 0.97 ALOX5 (0.46) ALOX5MAPTNPC1KMT2ASMN1; SMN2
SCHEMBL20127616 0.95 PLA2G2A (0.41) ALOX5MAPTNPC1KMT2ASMN1; SMN2
SCHEMBL17944859 0.95 MAPT (0.49) ALOX5MAPTNPC1KMT2ASMN1; SMN2
SCHEMBL20127628 0.94 PLA2G2A (0.45) ALOX5MAPTNPC1KMT2ASMN1; SMN2
SCHEMBL20127613 0.92 MAPT (0.46) ALOX5MAPTNPC1KMT2ASMN1; SMN2
SCHEMBL10122386 0.92 PLA2G2A (0.43) ALOX5MAPTNPC1KMT2ASMN1; SMN2
SCHEMBL19109902 0.92 MAPT (0.49) ALOX5MAPTNPC1KMT2ASMN1; SMN2
SCHEMBL25052552 0.91 ALOX5 (0.47) ALOX5MAPTNPC1KMT2ASMN1; SMN2
SCHEMBL13057803 0.91 MAPT (0.52) MAPTNPC1KMT2ASMN1; SMN2KDM4E
SCHEMBL10122392 0.90 PLA2G2A (0.46) ALOX5MAPTNPC1KMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180208836-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2018-07-26 US disclosed
US-20180208836-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2018-07-26 US disclosed
US-20180130968-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2018-05-10 US disclosed
US-20180130968-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2018-05-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180130968-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE RER1, NR0B1, NR2E1 ALOX5 4115/4885MAPT 3500/4885NPC1 1202/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.