SCHEMBL20127628

SCHEMBL20127628

c1cc(-c2ccc3c4ccccc4c4ccccc4c3c2)cc(-c2c3ccccc3c(-c3ccc4oc5c(ccc6c7ccccc7oc65)c4c3)c3ccccc23)c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLA2G2A P14555 4/20 0.45
PLA2G4A P47712 4/20 0.45
PLA2G10 O15496 1/20 0.45
ALOX5 P09917 2/20 0.43
MAPT P10636 3/20 0.39
NPC1 O15118 2/20 0.39
KDM4E B2RXH2 2/20 0.39
MEN1 O00255 2/20 0.39
ALDH1A1 P00352 2/20 0.39
HPGD P15428 2/20 0.39
KMT2A Q03164 2/20 0.39
RAB9A P51151 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
AHR P35869 3/20 0.36
GGPS1 O95749 1/20 0.35
PRKDC P78527 2/20 0.35
PGR P06401 1/20 0.35
DYRK1A Q13627 1/20 0.34
CASP3 P42574 1/20 0.34
SENP7 Q9BQF6 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20127632 0.95 PLA2G2A (0.46) PLA2G2APLA2G4APLA2G10ALOX5MAPT
SCHEMBL10122398 0.94 PLA2G2A (0.48) PLA2G2APLA2G4APLA2G10ALOX5MAPT
SCHEMBL10122425 0.94 PLA2G2A (0.48) PLA2G2APLA2G4APLA2G10ALOX5MAPT
SCHEMBL10122435 0.94 PLA2G2A (0.48) PLA2G2APLA2G4APLA2G10ALOX5MAPT
SCHEMBL23509072 0.94 PLA2G2A (0.49) PLA2G2APLA2G4APLA2G10ALOX5MAPT
SCHEMBL20127601 0.94 ALOX5 (0.44) PLA2G2APLA2G4APLA2G10ALOX5MAPT
SCHEMBL25052546 0.94 PLA2G2A (0.49) PLA2G2APLA2G4APLA2G10ALOX5MAPT
SCHEMBL10122436 0.93 PLA2G2A (0.47) PLA2G2APLA2G4APLA2G10ALOX5MAPT
SCHEMBL10122642 0.93 PLA2G2A (0.47) PLA2G2APLA2G4APLA2G10ALOX5MAPT
SCHEMBL10122420 0.93 PLA2G2A (0.47) PLA2G2APLA2G4APLA2G10ALOX5MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180208836-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2018-07-26 US disclosed
US-20180208836-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2018-07-26 US disclosed
US-20180130968-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2018-05-10 US disclosed
US-20180130968-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2018-05-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180130968-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE RER1, NR0B1, NR2E1 PLA2G2A 2960/4885PLA2G4A 3780/4885PLA2G10 4476/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.