SCHEMBL20127865

SCHEMBL20127865

Cc1cc(-c2ccccc2)cc2c1sc1ccccc12

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.49
MAPT P10636 5/20 0.49
L3MBTL1 Q9Y468 3/20 0.49
POLB P06746 2/20 0.49
TNKS O95271 1/20 0.49
TNKS2 Q9H2K2 1/20 0.49
HCRTR1 O43613 1/20 0.49
LMNA P02545 1/20 0.49
RAB9A P51151 3/20 0.44
ATM Q13315 1/20 0.44
KDM4E B2RXH2 1/20 0.44
GPR3 P46089 1/20 0.43
LIMK1 P53667 1/20 0.39
ALOX5 P09917 1/20 0.39
HPGD P15428 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
PIM3 Q86V86 1/20 0.35
PTPN1 P18031 1/20 0.35
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13689762 0.88 LIMK1 (0.48) ALDH1A1MAPTL3MBTL1POLBTNKS
SCHEMBL23331861 0.87 MAPT (0.48) ALDH1A1MAPTL3MBTL1POLBTNKS
SCHEMBL10442347 0.84 L3MBTL1 (0.40) ALDH1A1MAPTL3MBTL1POLBTNKS
SCHEMBL17416272 0.81 TNKS (0.50) ALDH1A1MAPTL3MBTL1TNKSTNKS2
SCHEMBL20821560 0.81 ALDH1A1 (0.46) ALDH1A1MAPTL3MBTL1POLBTNKS
SCHEMBL22725232 0.81 MAPT (0.44) ALDH1A1MAPTL3MBTL1POLBTNKS
SCHEMBL14797839 0.80 MAPT (0.53) ALDH1A1MAPTL3MBTL1POLBTNKS
SCHEMBL30278837 0.80 MAPT (0.53) ALDH1A1MAPTL3MBTL1POLBTNKS
SCHEMBL25991422 0.80 TNKS (0.47) ALDH1A1MAPTL3MBTL1POLBTNKS
SCHEMBL21042192 0.79 TNKS (0.49) ALDH1A1MAPTL3MBTL1POLBTNKS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11678566-B2 Organometallic compound and organic light-emitting device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-06-13 US disclosed
US-11678566-B2 Organometallic compound and organic light-emitting device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-06-13 US disclosed
EP-3670520-B1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE ORGANOMETALLIC COMPOUND, AND DIAGNOSTIC COMPOSITION INCLUDING THE ORGANOMETALLIC COMPOUND SAMSUNG ELECTRONICS CO LTD (KR) 2022-01-12 EP disclosed
EP-3770166-B1 ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO LTD (KR) 2021-10-06 EP disclosed
EP-3712145-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING SUCH COMPOUND Samsung Electronics Co., Ltd. (KR) 2020-09-23 EP disclosed
US-20180130964-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING ORGANOMETALLIC COMPOUND, AND DIAGNOSTIC COMPOSITION INCLUDING ORGANOMETALLIC COMPOUND SAMSUNG ELECTRONICS CO., LTD. (KR) 2018-05-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11678566-B2 Organometallic compound and organic light-emitting device including the same L1CAM, AP1M1, PYM1 ALDH1A1 368/4885MAPT 1337/4885L3MBTL1 7/4885
US-20180130964-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING ORGANOMETALLIC COMPOUND, AND DIAGNOSTIC COMPOSITION INCLUDING ORGANOMETALLIC COMPOUND ORC3, OCIAD1, LEF1 ALDH1A1 95/4885MAPT 1077/4885L3MBTL1 123/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.