SCHEMBL22725232

SCHEMBL22725232

Cc1ccc2c(c1)sc1cc(-c3cc(C)c4sc5ccccc5c4c3)ccc12

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.44
ALDH1A1 P00352 6/20 0.42
L3MBTL1 Q9Y468 4/20 0.42
POLB P06746 3/20 0.42
HCRTR1 O43613 1/20 0.42
LMNA P02545 1/20 0.42
RAB9A P51151 3/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
HPGD P15428 1/20 0.41
GPR3 P46089 1/20 0.39
ATM Q13315 1/20 0.38
KDM4E B2RXH2 1/20 0.38
TNKS O95271 2/20 0.37
TNKS2 Q9H2K2 2/20 0.37
ALOX5 P09917 1/20 0.36
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
NPC1 O15118 1/20 0.34
LIMK1 P53667 1/20 0.34
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20156869 0.84 MAPT (0.41) MAPTALDH1A1L3MBTL1POLBLMNA
SCHEMBL24000175 0.83 ALOX5 (0.36) MAPTALDH1A1L3MBTL1POLBHCRTR1
SCHEMBL20127865 0.81 ALDH1A1 (0.49) MAPTALDH1A1L3MBTL1POLBHCRTR1
SCHEMBL9917122 0.80 GPR3 (0.52) MAPTALDH1A1L3MBTL1POLBRAB9A
SCHEMBL9917189 0.80 GPR3 (0.52) MAPTALDH1A1L3MBTL1POLBRAB9A
SCHEMBL23046414 0.80 MAPT (0.39) MAPTALDH1A1L3MBTL1POLBHCRTR1
SCHEMBL808361 0.80 GPR3 (0.61) MAPTALDH1A1L3MBTL1POLBLMNA
SCHEMBL31677946 0.80 GPR3 (0.61) MAPTALDH1A1L3MBTL1POLBLMNA
SCHEMBL24221746 0.80 MAPT (0.40) MAPTALDH1A1L3MBTL1POLBRAB9A
SCHEMBL23240752 0.79 ALDH1A1 (0.55) MAPTALDH1A1L3MBTL1POLBRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200381628-A1 SPECIFIC LADDER TYPE COMPOUNDS FOR ORGANIC LIGHT EMITTING DEVICES IDEMITSU KOSAN CO., LTD. (JP) 2020-12-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200381628-A1 SPECIFIC LADDER TYPE COMPOUNDS FOR ORGANIC LIGHT EMITTING DEVICES APOL1, HMGB2, LOXL1 MAPT 1967/4885ALDH1A1 101/4885L3MBTL1 275/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.