Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | NR1H4 | Q96RI1 | 5/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7986748 | 1.00 | MMP8 (0.48) | MMP8LMNARAB9ANR1H4EPHX2 | |
| SCHEMBL7989719 | 0.88 | LMNA (0.42) | MMP8LMNARAB9AKMT2ACA12 | |
| SCHEMBL7989716 | 0.88 | LMNA (0.42) | MMP8LMNARAB9AKMT2ACA12 | |
| SCHEMBL7992658 | 0.87 | SMN1; SMN2 (0.56) | LMNARAB9AEPHX2KMT2AHPGD | |
| SCHEMBL7992662 | 0.87 | SMN1; SMN2 (0.56) | LMNARAB9AEPHX2KMT2AHPGD | |
| SCHEMBL7975312 | 0.79 | MAPT (0.47) | NR1H4EPHX2KMT2ACA1HPGD | |
| SCHEMBL7975315 | 0.79 | MAPT (0.47) | NR1H4EPHX2KMT2ACA1HPGD | |
| SCHEMBL7988109 | 0.79 | GRIN2D (0.49) | MMP8LMNARAB9AKMT2ACA12 | |
| SCHEMBL20488322 | 0.79 | NR1H4 (0.48) | MMP8NR1H4EPHX2KMT2ACA12 | |
| SCHEMBL20127882 | 0.77 | CA12 (0.46) | MMP8LMNARAB9AKMT2ACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265418-B1 | ANTICOAGULANTS | UBE INDUSTRIES, LTD. (JP) | 2001-07-24 | — | — | US | disclosed |
| EP-1020467-A1 | N-ACYLAMINO ACID AMIDE COMPOUNDS AND INTERMEDIATES FOR PREPARATION THEREOF | UBE INDUSTRIES LIMITED (JP) | 2000-07-19 | — | — | EP | disclosed |