Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 8/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.41 |
| ▸ | FOS | P01100 | 1/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | JUN | P05412 | 1/20 | 0.41 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.41 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.40 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.40 |
| ▸ | PNMT | P11086 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18182095 | 0.87 | CSNK2A1 (0.53) | CSNK2A1ALOX12MEN1KMT2ALMNA | |
| SCHEMBL18174199 | 0.81 | MAPT (0.49) | CSNK2A1ALOX12MEN1KMT2ALMNA | |
| SCHEMBL10274466 | 0.80 | CSNK2A1 (0.51) | CSNK2A1ALOX12MEN1KMT2ALMNA | |
| SCHEMBL20128505 | 0.80 | ALOX15 (0.43) | CSNK2A1ALOX15ALOX12NR3C1FOS | |
| SCHEMBL900877 | 0.77 | CSNK2A1 (0.47) | CSNK2A1ALOX12MEN1KMT2ALMNA | |
| SCHEMBL10980030 | 0.77 | SMN1; SMN2 (0.48) | CSNK2A1ALOX12MEN1KMT2ALMNA | |
| SCHEMBL20128504 | 0.76 | PNMT (0.66) | ALOX15ALOX12MEN1KMT2ALMNA | |
| SCHEMBL20061665 | 0.75 | PNMT (0.46) | ALOX15ALOX12MEN1KMT2ALMNA | |
| SCHEMBL10983789 | 0.74 | MEN1 (0.51) | CSNK2A1ALOX12MEN1KMT2ALMNA | |
| SCHEMBL12768177 | 0.73 | CSNK2A1 (0.70) | CSNK2A1MEN1KMT2ALMNAPNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180127402-A1 | ISOXAZOLYL SUBSTITUTED BENZIMIDAZOLES | CELLCENTRIC LTD (GB) | 2018-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180127402-A1 | ISOXAZOLYL SUBSTITUTED BENZIMIDAZOLES | EP300, HDAC3, HDAC1 | CSNK2A1 456/4885ALOX15 4701/4885ALOX12 4667/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.