Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CYP51A1 | Q16850 | 6/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CFTR | P13569 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.43 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17607341 | 0.98 | LMNA (0.49) | L3MBTL1LMNASMN1; SMN2TDP1TBXAS1 | |
| SCHEMBL9629718 | 0.95 | L3MBTL1 (0.51) | L3MBTL1LMNASMN1; SMN2TDP1TBXAS1 | |
| SCHEMBL9830214 | 0.89 | SMN1; SMN2 (0.53) | L3MBTL1LMNASMN1; SMN2TBXAS1GAA | |
| SCHEMBL906187 | 0.89 | SMN1; SMN2 (0.53) | L3MBTL1LMNASMN1; SMN2TBXAS1GAA | |
| SCHEMBL18473557 | 0.84 | L3MBTL1 (0.51) | L3MBTL1LMNASMN1; SMN2TDP1TBXAS1 | |
| SCHEMBL2573660 | 0.84 | SMN1; SMN2 (0.50) | L3MBTL1LMNASMN1; SMN2TBXAS1GAA | |
| SCHEMBL29024102 | 0.83 | LMNA (0.45) | L3MBTL1LMNASMN1; SMN2TDP1TBXAS1 | |
| SCHEMBL25003559 | 0.83 | L3MBTL1 (0.50) | L3MBTL1LMNASMN1; SMN2TDP1TBXAS1 | |
| SCHEMBL18842833 | 0.83 | L3MBTL1 (0.50) | L3MBTL1LMNASMN1; SMN2TDP1TBXAS1 | |
| SCHEMBL20940017 | 0.83 | L3MBTL1 (0.50) | L3MBTL1LMNASMN1; SMN2TDP1TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7964599-B2 | Therapeutic compounds | ALLERGAN, INC. (US) | 2011-06-21 | — | — | US | disclosed |
| US-20090281104-A1 | Therapeutic Compounds | ALLERGAN, INC. (US) | 2009-11-12 | — | — | US | disclosed |
| EP-2029518-A2 | CYCLOPENTANE-DERIVATIVES AND THEIR USE AS OCULAR HYPOTENSIVE AGENTS | Allergan, Inc. (US) | 2009-03-04 | — | — | EP | disclosed |
| US-7476755-B2 | Therapeutic compounds | ALLERGAN, INC. (US) | 2009-01-13 | — | — | US | disclosed |
| WO-2007130890-A2 | CYCLOPENTANE-DERIVATIVES AND THEIR USE AS OCULAR HYPOTENSIVE AGENTS | ALLERGAN, INC. (US) | 2007-11-15 | — | — | WO | disclosed |
| US-20070259929-A1 | Therapeutic Compounds | ALLERGAN, INC. | 2007-11-08 | — | — | US | disclosed |
| EP-0316783-B1 | PROCESS FOR THE PREPARATION OF HETERO-AROMATIC KETONES AND ALDEHYDES | BASF Aktiengesellschaft (DE) | 1992-03-18 | — | — | EP | disclosed |
| EP-0356843-A2 | Process for the preparation of heteroaromatic aldehydes and ketones | BASF Aktiengesellschaft (DE) | 1990-03-07 | — | — | EP | disclosed |
| EP-0316783-A1 | Process for the preparation of hetero-aromatic ketones and aldehydes | BASF Aktiengesellschaft (DE) | 1989-05-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070259929-A1 | Therapeutic Compounds | PIGO, CYC1, COXFA4L2 | L3MBTL1 3867/4885LMNA 1423/4885SMN1; SMN2 1920/4885 |
| US-20090281104-A1 | Therapeutic Compounds | SLC10A1, ABCB11, GUSB | L3MBTL1 3358/4885LMNA 2172/4885SMN1; SMN2 1306/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.