Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.76 |
| ▸ | LMNA | P02545 | 7/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.76 |
| ▸ | THRB | P10828 | 1/20 | 0.76 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.64 |
| ▸ | MEN1 | O00255 | 4/20 | 0.64 |
| ▸ | PKM | P14618 | 2/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | CCR6 | P51684 | 1/20 | 0.60 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | XBP1 | P17861 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20129478 | 1.00 | MAPT (0.76) | MAPTLMNAALDH1A1THRBMDM2 | |
| SCHEMBL20129849 | 1.00 | MAPT (0.76) | MAPTLMNAALDH1A1THRBMDM2 | |
| SCHEMBL20129821 | 0.95 | MAPT (0.70) | MAPTLMNAALDH1A1THRBMDM2 | |
| SCHEMBL10877147 | 0.92 | MAPT (0.79) | MAPTLMNAALDH1A1THRBMDM2 | |
| SCHEMBL19981480 | 0.89 | MAPT (0.63) | MAPTLMNAALDH1A1THRBMDM2 | |
| SCHEMBL20128529 | 0.88 | MAPT (0.62) | MAPTLMNAALDH1A1THRBMDM2 | |
| SCHEMBL18719822 | 0.88 | MAPT (0.67) | MAPTLMNAALDH1A1THRBMDM2 | |
| SCHEMBL17789566 | 0.88 | ALDH1A1 (0.62) | MAPTLMNAALDH1A1THRBMDM2 | |
| SCHEMBL18719857 | 0.87 | ALDH1A1 (0.65) | MAPTLMNAALDH1A1THRBKMT2A | |
| SCHEMBL31453743 | 0.84 | MAPT (0.57) | MAPTLMNAALDH1A1THRBMDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180126784-A1 | RUBBER COMPOSITION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2018-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180126784-A1 | RUBBER COMPOSITION | RER1, KPNB1, KPNA1 | MAPT 3342/4885LMNA 512/4885ALDH1A1 1232/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.