Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 4/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | NSD2 | O96028 | 4/20 | 0.54 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.51 |
| ▸ | PKLR | P30613 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6754556 | 0.82 | ALDH1A1 (0.69) | FABP4ALDH1A1TBXA2RMEN1POLB | |
| SCHEMBL27463917 | 0.81 | NSD2 (0.51) | FABP4ALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL3871903 | 0.81 | NSD2 (0.51) | FABP4ALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL386440 | 0.81 | NSD2 (0.57) | FABP4POLBNSD2PKLR | |
| SCHEMBL8488159 | 0.81 | CYP3A4 (0.59) | FABP4ALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL6867446 | 0.80 | APEX1 (0.55) | FABP4ALDH1A1TBXA2RNSD2HDAC4 | |
| SCHEMBL15515613 | 0.79 | HDAC4 (0.79) | FABP4ALDH1A1TBXA2RMEN1POLB | |
| SCHEMBL15507473 | 0.79 | HDAC4 (0.79) | FABP4ALDH1A1TBXA2RMEN1POLB | |
| SCHEMBL15515796 | 0.79 | HDAC4 (0.79) | FABP4ALDH1A1TBXA2RMEN1POLB | |
| SCHEMBL591663 | 0.79 | HDAC4 (0.79) | FABP4ALDH1A1TBXA2RMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0576480-B1 | ASSAY FOR THE DETERMINATION OF ESTER SUBSTRATES | BRITISH TECH GROUP (GB) | 1998-06-03 | — | — | EP | claimed |
| US-5512429-A | Assay for enzyme activity | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1996-04-30 | — | — | US | claimed |
| EP-0493426-B1 | ASSAY FOR ENZYME ACTIVITY | BRITISH TECH GROUP (GB) | 1995-11-08 | — | — | EP | claimed |
| US-5449607-A | Assay for the quantitative determination of substrates capable of undergoing enzymatic hydrolysis to release long-chain fatty acids | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1995-09-12 | — | — | US | claimed |
| EP-0576480-A1 | ASSAY FOR THE DETERMINATION OF ESTER SUBSTRATES | BRITISH TECHNOLOGY GROUP LTD (GB) | 1994-01-05 | — | — | EP | claimed |
| WO-1992016847-A1 | ASSAY FOR THE DETERMINATION OF ESTER SUBSTRATES | BRITISH TECHNOLOGY GROUP LTD (GB) | 1992-10-01 | — | — | WO | claimed |
| WO-1991004338-A1 | ASSAY FOR ENZYME ACTIVITY | BRITISH TECHNOLOGY GROUP PLC (GB) | 1991-04-04 | — | — | WO | claimed |
| CN-117907494-A | Application of D-2-phosphoglycerate and L-propionyl carnitine in judging whether female buffalo is in oestrus | 中国农业科学院北京畜牧兽医研究所 | 2024-04-19 | — | — | CN | disclosed |
| US-10443081-B2 | Methods for the expression of peptides and proteins | NUMAFERM GMBH (DE) | 2019-10-15 | — | — | US | disclosed |
| EP-2986633-B1 | METHODS FOR THE EXPRESSION OF PEPTIDES AND PROTEINS | NUMAFERM GMBH (DE) | 2018-01-31 | — | — | EP | disclosed |
| US-20160138066-A1 | METHODS FOR THE EXPRESSION OF PEPTIDES AND PROTEINS | NUMAFERM GMBH (DE) | 2016-05-19 | — | — | US | disclosed |
| CN-105473609-A | Methods for expression of peptides and proteins | HEINRICH HEINE UNIV DUSSELDORF | 2016-04-06 | — | — | CN | disclosed |
| US-20140378668-A1 | Tyrosine Bioconjugation through Aqueous Ene-Like Reactions | SCRIPPS RESEARCH INST (US) | 2014-12-25 | — | — | US | disclosed |
| EP-1529213-A1 | THE METHOD AND APPARATUS FOR DETERMINING THE NUMBER OF LIVING CELLS IN A TEST FLUID | Nederlandse Organisatie voor toegepast-natuurwetenschappelijk Onderzoek TNO (NL) | 2005-05-11 | — | — | EP | disclosed |
| WO-2004015413-A1 | THE METHOD AND APPARATUS FOR DETERMINING THE NUMBER OF LIVING CELLS IN A TEST FLUID | NEDERLANDSE ORGANISATIE VOOR TOEGEPAST- NATUURWETENSCHAPPELIJK ONDERZOEK TNO (NL) | 2004-02-19 | — | — | WO | disclosed |
| EP-0576480-B1 | ASSAY FOR THE DETERMINATION OF ESTER SUBSTRATES | BRITISH TECH GROUP (GB) | 1998-06-03 | — | — | EP | disclosed |
| US-5512429-A | Assay for enzyme activity | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1996-04-30 | — | — | US | disclosed |
| EP-0493426-B1 | ASSAY FOR ENZYME ACTIVITY | BRITISH TECH GROUP (GB) | 1995-11-08 | — | — | EP | disclosed |
| US-5449607-A | Assay for the quantitative determination of substrates capable of undergoing enzymatic hydrolysis to release long-chain fatty acids | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1995-09-12 | — | — | US | disclosed |
| WO-1991004338-A1 | ASSAY FOR ENZYME ACTIVITY | BRITISH TECHNOLOGY GROUP PLC (GB) | 1991-04-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140378668-A1 | Tyrosine Bioconjugation through Aqueous Ene-Like Reactions | TYR, DNPEP, TH | FABP4 2407/4885ALDH1A1 4268/4885TBXA2R 4315/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.