SCHEMBL386440

SCHEMBL386440

Nc1ccc(S(=O)(=O)NCC(=O)O)c2ccccc12

nearest known ligand 0.68

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
NSD2 O96028 8/20 0.57
ALPL P05186 1/20 0.51
POLB P06746 1/20 0.51
MMP1 P03956 1/20 0.49
GAA P10253 1/20 0.49
MMP12 P39900 1/20 0.49
FABP4 P15090 4/20 0.48
PKLR P30613 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9751654 0.90 NSD2 (0.51) NSD2ALPLPOLBMMP1GAA
SCHEMBL8087336 0.83 NSD2 (0.49) NSD2FABP4
SCHEMBL2013174 0.81 FABP4 (0.71) NSD2POLBFABP4PKLR
SCHEMBL6077738 0.78 CASP1 (0.56) ALPLPOLBMMP1GAAMMP12
SCHEMBL8968288 0.78 CYP3A4 (0.61) NSD2
SCHEMBL11686439 0.78 NSD2 (0.86) NSD2
SCHEMBL1366996 0.77 NSD2 (0.55) NSD2
SCHEMBL11573784 0.77 NSD2 (0.59) NSD2FABP4
SCHEMBL8864869 0.77 NSD2 (0.54) NSD2
SCHEMBL8842858 0.76 NSD2 (0.45) NSD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 430 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260048152-A1 GEMCITABINE INORGANIC-ORGANIC HYBRID NANOPARTICLES KARLSRUHER INSTITUT FUER TECH KOERPERSCHAFT DES OEFFENTLICHEN RECHTS (DE) 2026-02-19 US claimed
US-12145951-B2 Inorganic-organic hybrid compounds including organic platinum-containing anions, for use in medicine KARLSRUHER INSTITUT FUR TECHNOLOGIE (DE) 2024-11-19 US claimed
US-20210292353-A1 INORGANIC-ORGANIC HYBRID COMPOUNDS INCLUDING ORGANIC PLATINUM-CONTAINING ANIONS, FOR USE IN MEDICINE MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2021-09-23 US claimed
US-20170112948-A1 Inorganic-organic hybrid compound Karlsruher Institut für Technologie (DE) 2017-04-27 US claimed
US-8480928-B2 Inorganic-organic composite luminophore KARLSRUHER INSTITUT FUR TECHNOLOGIE (KIT) (DE) 2013-07-09 US claimed
US-20110198538-A1 INORGANIC-ORGANIC COMPOSITE LUMINOPHORE Karlsruher Institut for Technologie (KIT) (DE) 2011-08-18 US claimed
WO-2009018368-A1 COMBINATION TREATMENT OF NMDA (N-METHYL-D-ASPARTATE)-ENHANCER, GLYCINE TRANSPORTER INHIBITOR, D-AMINO ACID OXIDASE INHIBITOR (DAAOI) FOR NEUROPSYCHIATRIC DISORDERS LOS ANGELES BIOMEDICAL RESEARCH INSTITUTE AT HARBOR-UCLA MEDICAL CENTER (US) 2009-02-05 WO claimed
US-5541633-A Ink jet printing of concealed images on carbonless paper XEROX CORPORATION (US) 1996-07-30 US claimed
US-5286286-A Containing diethylene glycol monobutyl ether, glycerol, and a dansyl or porphyrin chromophores XEROX CORPORATION (US) 1994-02-15 US claimed
US-12637489-B2 Silicon containing modified nucleotide analogs Singular Genomics Systems, Inc. (US) 2026-05-26 US disclosed
US-12630808-B2 Modified archaeal family b polymerases Singular Genomics Systems, Inc. (US) 2026-05-19 US disclosed
US-20260125660-A1 MODIFIED ARCHAEAL FAMILY B POLYMERASES SINGULAR GENOMICS SYSTEMS INC (US) 2026-05-07 US disclosed
US-20260110028-A1 NUCLEOTIDE ANALOGS AND USES THEREOF SINGULAR GENOMICS SYSTEMS INC (US) 2026-04-23 US disclosed
US-12595508-B2 Nucleotide cleavable linkers and uses thereof Singular Genomics Systems, Inc. (US) 2026-04-07 US disclosed
US-5286286-A Containing diethylene glycol monobutyl ether, glycerol, and a dansyl or porphyrin chromophores XEROX CORPORATION (US) 1994-02-15 US disclosed
EP-0547142-A1 SOLID SUPPORT SYNTHESIS OF 3'-TAILED OLIGONUCLEOTIDES VIA A LINKING MOLECULE EPOCH PHARMACEUTICALS, INC. (US) 1993-06-23 EP disclosed
WO-1992003464-A1 SOLID SUPPORT SYNTHESIS OF 3'-TAILED OLIGONUCLEOTIDES VIA A LINKING MOLECULE MICROPROBE CORPORATION (US) 1992-03-05 WO disclosed
US-4578499-A CHEMILUMINESCENT REAGENTS WAKO PURE CHEMICAL INDUSTRIES LTD. (JP) 1986-03-25 US disclosed
US-4314936-A BY MEASUREM,ENT OF FLUORESENCE YEDA RESEARCH AND DEVELOPMENT CO., LTD. (IL) 1982-02-09 US disclosed
US-4046877-A HUMAN SERUM PREALBUMIN SYNTEX (U.S.A.) INC. (US) 1977-09-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12630808-B2 Modified archaeal family b polymerases SSU72, POLB, POLQ NSD2 2331/4885ALPL 725/4885POLB 2/4885
US-12595508-B2 Nucleotide cleavable linkers and uses thereof NSUN2, CCRL2, NOP2 NSD2 2439/4885ALPL 3426/4885POLB 160/4885
US-12637489-B2 Silicon containing modified nucleotide analogs NSUN2, POLR2H, POLH NSD2 2880/4885ALPL 2738/4885POLB 7/4885
US-20260048152-A1 GEMCITABINE INORGANIC-ORGANIC HYBRID NANOPARTICLES GOT1, RNMT, GNAO1 NSD2 1943/4885ALPL 135/4885POLB 149/4885
US-20170112948-A1 Inorganic-organic hybrid compound SLCO4C1, SLCO2A1, SLCO1A2 NSD2 3368/4885ALPL 111/4885POLB 3337/4885
US-20260110028-A1 NUCLEOTIDE ANALOGS AND USES THEREOF POLL, POLB, POLN NSD2 495/4885ALPL 1025/4885POLB 2/4885
US-20260125660-A1 MODIFIED ARCHAEAL FAMILY B POLYMERASES DNMT3A, POLB, POLM NSD2 888/4885ALPL 137/4885POLB 2/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.