Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | AHR | P35869 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | EIF2AK2 | P19525 | 6/20 | 0.49 |
| ▸ | CCR6 | P51684 | 1/20 | 0.47 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11287982 | 0.84 | IMPDH2 (0.60) | IMPDH2MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL31060312 | 0.76 | IMPDH2 (1.00) | IMPDH2MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL19100789 | 0.76 | IMPDH2 (0.64) | IMPDH2MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL14758442 | 0.75 | KDM4E (0.55) | IMPDH2MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL18457731 | 0.75 | MAPT (0.55) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL17383846 | 0.75 | IMPDH2 (0.73) | IMPDH2MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL1720216 | 0.74 | CYP1A2 (0.55) | IMPDH2MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL18392175 | 0.73 | CCR6 (0.58) | IMPDH2MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL10067256 | 0.73 | MEN1 (0.56) | IMPDH2MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL13561069 | 0.73 | LMNA (0.66) | IMPDH2MEN1KMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102006902-B | Anti-infectious catheter | ANGIOTECH INTERNATIONAL AG (CH) | 2015-10-07 | — | — | CN | disclosed |
| US-20110150961-A1 | ANTI-INFECTIVE CATHETERS | ANGIOTECH INTERNATIONAL AG (CH) | 2011-06-23 | — | — | US | disclosed |
| CN-102006902-A | Anti-infective catheters | ANGIOTECH INT AG | 2011-04-06 | — | — | CN | disclosed |
| CN-1186339-C | Pyrimidinyl methyl indole derivatives with antibacterial activity | BASLYER PHARMACEUTICAL AG (CH) | 2005-01-26 | — | — | CN | disclosed |
| CN-1186339-C | Pyrimidinyl methyl indole derivatives with antibacterial activity | BASLYER PHARMACEUTICAL AG (CH) | 2005-01-26 | — | — | CN | disclosed |
| US-6703397-B2 | REACTING A NITRILE GROUP CONTAINING INDOLE DERIVEATIVE WITH GUANIDINE OR SALT; USEFUL AS PROHYLAXIS OR THERAPEUTICAL TREATMENT OF INFECTIOUS DISEASES | BASILEA PHARMACEUTICA AG (CH) | 2004-03-09 | — | — | US | disclosed |
| US-20030119857-A1 | Pyrimidinyl methyl indole derivatives with antibacterial activity | BASILEA PHARMACEUTICA AG (CH) | 2003-06-26 | — | — | US | disclosed |
| CN-1426408-A | Pyrimidinyl methyl indole derivatives with antibacterial activity | BASLYER PHARMACEUTICAL AG (CH) | 2003-06-25 | — | — | CN | disclosed |
| CN-1426408-A | Pyrimidinyl methyl indole derivatives with antibacterial activity | BASLYER PHARMACEUTICAL AG (CH) | 2003-06-25 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110150961-A1 | ANTI-INFECTIVE CATHETERS | NACA, PUF60, POLR1C | IMPDH2 1038/4885MEN1 4611/4885KMT2A 2534/4885 |
| US-20030119857-A1 | Pyrimidinyl methyl indole derivatives with antibacterial activity | IDO1, IDO2, AANAT | IMPDH2 116/4885MEN1 4153/4885KMT2A 1379/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.