SCHEMBL201344

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL202342	0.88	ALDH1A1 (0.55)	ALDH1A1KMT2AMEN1NPC1RAB9A
	SCHEMBL416823	0.84	POLB (0.55)	ALDH1A1KMT2ANPC1RAB9ACYP1A2
	SCHEMBL28597048	0.81	NPC1 (0.64)	ALDH1A1KMT2AMEN1NPC1RAB9A
	SCHEMBL2351707	0.80	RAB9A (0.70)	ALDH1A1KMT2AMEN1NPC1RAB9A
	SCHEMBL9402456	0.80	HDAC8 (0.69)	ALDH1A1KMT2AMEN1NPC1RAB9A
	SCHEMBL8921124	0.80	L3MBTL1 (0.50)	ALDH1A1KMT2AMEN1NPC1RAB9A
	SCHEMBL2756458	0.80	MAPT (0.63)	ALDH1A1KMT2AMEN1NPC1RAB9A
	SCHEMBL28668589	0.79	ALDH1A1 (0.77)	ALDH1A1KMT2AMEN1NPC1RAB9A
	SCHEMBL202343	0.78	ALDH1A1 (0.54)	ALDH1A1KMT2AMEN1NPC1RAB9A
	SCHEMBL21685418	0.77	KDM4E (0.56)	ALDH1A1KMT2AMEN1TSHRKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.