Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 1/20 | 0.41 |
| ▸ | GABRD | O14764 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.41 |
| ▸ | GABRE | P78334 | 1/20 | 0.41 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.41 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.41 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.41 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.41 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.38 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | LDHA | P00338 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31716869 | 0.87 | GABRP (0.38) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL24087313 | 0.85 | NNMT (0.41) | MAOBL3MBTL1DYRK1AFASNTDP1 | |
| SCHEMBL2013520 | 0.83 | TRIM33 (0.38) | MAOBKDM4EALDH1A1FASNKDR | |
| SCHEMBL1796361 | 0.83 | MAOB (0.40) | MAOBL3MBTL1DYRK1AFASNMCHR1 | |
| SCHEMBL29229563 | 0.80 | MAOB (0.43) | APOBEC3AAPOBEC3GMAOBKDM4EALDH1A1 | |
| SCHEMBL25149802 | 0.80 | DYRK1A (0.36) | APOBEC3AAPOBEC3GMAOBKDM4EL3MBTL1 | |
| SCHEMBL29229549 | 0.80 | POLQ (0.41) | KDM4EALDH1A1PKMMYCNAMPT | |
| SCHEMBL27305869 | 0.78 | KDM4C (0.41) | APOBEC3AAPOBEC3GMAOBKDM4EALDH1A1 | |
| SCHEMBL12653263 | 0.76 | DYRK1A (0.37) | MAOBALDH1A1GAAPKML3MBTL1 | |
| SCHEMBL12618940 | 0.76 | DYRK1A (0.37) | MAOBALDH1A1GAAPKML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011073316-A1 | 4-ARYL-BUTANE-1,3-DIAMIDES | NOVARTIS AG (CH) | 2011-06-23 | — | — | WO | disclosed |