Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | TNKS | O95271 | 7/20 | 0.44 |
| ▸ | PARP1 | P09874 | 7/20 | 0.44 |
| ▸ | PARP2 | Q9UGN5 | 7/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20135252 | 1.00 | TP53 (0.47) | TP53HDAC3CYP2C9HDAC1HDAC6 | |
| SCHEMBL20135446 | 0.92 | TP53 (0.51) | TP53HDAC3CYP2C9HDAC1HDAC6 | |
| SCHEMBL20135447 | 0.92 | TP53 (0.51) | TP53HDAC3CYP2C9HDAC1HDAC6 | |
| SCHEMBL20134826 | 0.92 | MAPT (0.46) | TP53HDAC3CYP2C9HDAC1HDAC6 | |
| SCHEMBL20134936 | 0.92 | TNKS (0.42) | TP53HDAC3CYP2C9HDAC1HDAC6 | |
| SCHEMBL20134822 | 0.92 | MAPT (0.46) | TP53HDAC3CYP2C9HDAC1HDAC6 | |
| SCHEMBL20134938 | 0.92 | TNKS (0.42) | TP53HDAC3CYP2C9HDAC1HDAC6 | |
| SCHEMBL20134784 | 0.89 | TP53 (0.53) | TP53HDAC3CYP2C9HDAC1HDAC6 | |
| SCHEMBL20134783 | 0.89 | TP53 (0.53) | TP53HDAC3CYP2C9HDAC1HDAC6 | |
| SCHEMBL20135474 | 0.83 | TP53 (0.41) | TP53MAPTTSHRTNKSPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10407408-B2 | Imide derivatives and use thereof as medicine | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2019-09-10 | — | — | US | disclosed |
| US-20190077787-A1 | NOVEL IMIDE DERIVATIVES AND USE THEREOF AS MEDICINE | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2019-03-14 | — | — | US | disclosed |
| EP-3321256-A1 | NOVEL IMIDE DERIVATIVES AND USE THEREOF AS MEDICINE | Mitsubishi Tanabe Pharma Corporation (JP) | 2018-05-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190077787-A1 | NOVEL IMIDE DERIVATIVES AND USE THEREOF AS MEDICINE | MMP9, MMP10, MMP1 | TP53 4082/4885HDAC3 277/4885CYP2C9 139/4885 |
| US-10407408-B2 | Imide derivatives and use thereof as medicine | MMP9, MMP2, MMP1 | TP53 3806/4885HDAC3 373/4885CYP2C9 97/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.