Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNK | O75909 | 4/20 | 0.52 |
| ▸ | CDK12 | Q9NYV4 | 4/20 | 0.52 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.48 |
| ▸ | SYK | P43405 | 6/20 | 0.43 |
| ▸ | NOS1 | P29475 | 3/20 | 0.42 |
| ▸ | NOS2 | P35228 | 3/20 | 0.42 |
| ▸ | NOS3 | P29474 | 2/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.42 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.41 |
| ▸ | CCR6 | P51684 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29688795 | 1.00 | CCNK (0.52) | CCNKCDK12PAK1SYKNOS1 | |
| SCHEMBL20135502 | 1.00 | CCNK (0.52) | CCNKCDK12PAK1SYKNOS1 | |
| SCHEMBL29688787 | 0.87 | CCNK (0.49) | CCNKCDK12PAK1SYKNOS1 | |
| SCHEMBL20135102 | 0.87 | CCNK (0.49) | CCNKCDK12PAK1SYKNOS1 | |
| SCHEMBL20135100 | 0.87 | CCNK (0.49) | CCNKCDK12PAK1SYKNOS1 | |
| SCHEMBL20134897 | 0.86 | CCNK (0.49) | CCNKCDK12PAK1SYKNOS1 | |
| SCHEMBL29688872 | 0.86 | CCNK (0.49) | CCNKCDK12PAK1SYKNOS1 | |
| SCHEMBL20135119 | 0.86 | CCNK (0.49) | CCNKCDK12PAK1SYKNOS1 | |
| SCHEMBL29688803 | 0.86 | CCNK (0.49) | CCNKCDK12PAK1SYKNOS1 | |
| SCHEMBL20134895 | 0.86 | CCNK (0.49) | CCNKCDK12PAK1SYKNOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10407408-B2 | Imide derivatives and use thereof as medicine | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2019-09-10 | — | — | US | disclosed |
| US-10407408-B2 | Imide derivatives and use thereof as medicine | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2019-09-10 | — | — | US | disclosed |
| US-20190077787-A1 | NOVEL IMIDE DERIVATIVES AND USE THEREOF AS MEDICINE | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2019-03-14 | — | — | US | disclosed |
| US-20190077787-A1 | NOVEL IMIDE DERIVATIVES AND USE THEREOF AS MEDICINE | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2019-03-14 | — | — | US | disclosed |
| EP-3321256-A1 | NOVEL IMIDE DERIVATIVES AND USE THEREOF AS MEDICINE | Mitsubishi Tanabe Pharma Corporation (JP) | 2018-05-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190077787-A1 | NOVEL IMIDE DERIVATIVES AND USE THEREOF AS MEDICINE | MMP9, MMP10, MMP1 | CCNK 2686/4885CDK12 2429/4885PAK1 2256/4885 |
| US-10407408-B2 | Imide derivatives and use thereof as medicine | MMP9, MMP2, MMP1 | CCNK 2435/4885CDK12 2332/4885PAK1 2509/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.