Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | NT5E | P21589 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | MAOA | P21397 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28853371 | 0.78 | CYP3A4 (0.39) | ALDH1A1TP53CYP3A4TDP1CASP1 | |
| SCHEMBL28300971 | 0.75 | MAOA (0.34) | ALDH1A1TP53CYP3A4TDP1CASP1 | |
| SCHEMBL27487602 | 0.69 | ALDH1A1 (0.42) | ALDH1A1NT5ETP53CYP3A4TDP1 | |
| Sulfuric Acid SCHEMBL8521101 | 0.69 | ALDH1A1 (0.35) | ALDH1A1NT5ETP53CYP3A4TDP1 | |
| SCHEMBL9280690 | 0.68 | ALDH1A1 (0.36) | ALDH1A1NT5ETP53CYP3A4TDP1 | |
| SCHEMBL8954074 | 0.66 | DHFR (0.55) | ALDH1A1TP53CYP3A4TDP1CASP1 | |
| SCHEMBL11301972 | 0.66 | ALDH1A1 (0.41) | ALDH1A1NT5ETP53CYP3A4TDP1 | |
| SCHEMBL28355210 | 0.66 | MEN1 (0.38) | ALDH1A1NT5ETP53CYP3A4TDP1 | |
| SCHEMBL1270822 | 0.65 | ALDH1A1 (0.45) | ALDH1A1NT5ETP53CYP3A4TDP1 | |
| SCHEMBL29566314 | 0.65 | ALDH1A1 (0.45) | ALDH1A1NT5ETP53CYP3A4TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150166656-A1 | MONOCLONAL ANTIBODIES TO GASTRIN HORMONE | APHTON CORPORATION | 2015-06-18 | — | — | US | disclosed |
| US-8808695-B2 | Monoclonal antibodies to progastrin | CANCER ADVANCES, INC. (US) | 2014-08-19 | — | — | US | disclosed |
| EP-2567974-A2 | Monoclonal antibodies to progastrin | Cancer Advances, Inc., (US) | 2013-03-13 | — | — | EP | disclosed |
| EP-1794586-B1 | MONOCLONAL ANTIBODIES TO PROGASTRIN | CANCER ADVANCES INC (US) | 2013-01-30 | — | — | EP | disclosed |
| US-20120156205-A1 | MONOCLONAL ANTIBODIES TO PROGASTRIN | GRIMES STEPHEN (US) | 2012-06-21 | — | — | US | disclosed |
| US-8158128-B2 | Monoclonal antibodies to progastrin | CANCER ADVANCES, INC. (US) | 2012-04-17 | — | — | US | disclosed |
| US-7964371-B2 | Gastrin hormone immunoassays | CANCER ADVANCES, INC. (US) | 2011-06-21 | — | — | US | disclosed |
| US-20070249005-A1 | Gastrin hormone immunoassays | APHTON CORPORATION | 2007-10-25 | — | — | US | disclosed |
| US-20070248608-A1 | Monoclonal Antibodies to Progastrin | APHTON CORPORATION (US) | 2007-10-25 | — | — | US | disclosed |
| US-7235376-B2 | Gastrin hormone immunoassays | RECEPTOR BIOLOGIX, INC. (US) | 2007-06-26 | — | — | US | disclosed |
| EP-1794586-A1 | MONOCLONAL ANTIBODIES TO PROGASTRIN | APHTON CORPORATION (US) | 2007-06-13 | — | — | EP | disclosed |
| US-20070066809-A1 | Monoclonal antibodies to gastrin hormone | CANCER ADVANCES, INC. | 2007-03-22 | — | — | US | disclosed |
| EP-1730193-A2 | MONOCLONAL ANTIBODIES TO GASTRIN HORMONE | Receptor Biologix, Inc. (US) | 2006-12-13 | — | — | EP | disclosed |
| WO-2006032980-A1 | MONOCLONAL ANTIBOLIES TO PROGASTRIN | RECEPTOR BIOLOGIX, INC. (US) | 2006-03-30 | — | — | WO | disclosed |
| US-20060020119-A1 | Monoclonal antibodies to gastrin hormone | CANCER ADVANCES, INC. | 2006-01-26 | — | — | US | disclosed |
| EP-1608984-A2 | GASTRIN HORMONE IMMUNOASSAYS | APHTON CORPORATION (US) | 2005-12-28 | — | — | EP | disclosed |
| WO-2005095459-A2 | MONOCLONAL ANTIBODIES TO GASTRIN HORMONE | RECEPTOR BIOLOGIX, INC. (US) | 2005-10-13 | — | — | WO | disclosed |
| US-20050069966-A1 | Using gastrin concentration as diagnostic tool in detetction and treatment of gastrointestinal disorders | CANCER ADVANCES, INC. | 2005-03-31 | — | — | US | disclosed |
| WO-2004088326-A2 | GASTRIN HORMONE IMMUNOASSAYS | APHTON CORPORATION (US) | 2004-10-14 | — | — | WO | disclosed |