SCHEMBL28853371

SCHEMBL28853371

Cc1cc(-c2ccc(N)cc2)c(C)c(C)c1N(C)C

nearest known ligand 0.45

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 5/20 0.39
ALDH1A1 P00352 4/20 0.39
TDP1 Q9NUW8 4/20 0.39
TP53 P04637 2/20 0.39
ALOX15 P16050 1/20 0.39
MAPK1 P28482 1/20 0.39
DHFR P00374 1/20 0.37
CA12 O43570 1/20 0.34
CA9 Q16790 1/20 0.34
MAOB P27338 2/20 0.33
MAOA P21397 2/20 0.33
CASP1 P29466 2/20 0.33
TSHR P16473 2/20 0.33
ACHE P22303 1/20 0.33
RPS6KA3 P51812 1/20 0.32
PDE10A Q9Y233 1/20 0.31
TAAR1 Q96RJ0 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28300971 0.82 MAOA (0.34) CYP3A4ALDH1A1TDP1TP53ALOX15
SCHEMBL28211221 0.80 CYP3A4 (0.42) CYP3A4ALDH1A1TDP1TP53DHFR
SCHEMBL29236426 0.80 ALDH1A1 (0.42) CYP3A4ALDH1A1TDP1TP53ALOX15
SCHEMBL186971 0.79 POLB (0.41) CYP3A4ALDH1A1TDP1TP53DHFR
SCHEMBL2013577 0.78 ALDH1A1 (0.40) CYP3A4ALDH1A1TDP1TP53ALOX15
SCHEMBL8954074 0.75 DHFR (0.55) CYP3A4ALDH1A1TDP1TP53DHFR
SCHEMBL8954051 0.73 CYP3A4 (0.53) CYP3A4ALDH1A1TDP1TP53DHFR
SCHEMBL21548 0.72 CYP3A4 (0.40) CYP3A4ALDH1A1TDP1TP53ALOX15
SCHEMBL27687136 0.72 CYP3A4 (0.40) CYP3A4ALDH1A1TDP1TP53ALOX15
Hydrochloric Acid SCHEMBL526312 0.70 TDP1 (0.39) CYP3A4ALDH1A1TDP1TP53ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115160374-A Stable OLED materials and devices with improved stability 通用显示公司 2022-10-11 CN disclosed