Known targets — ChEMBL curated mechanism
CHRM1CHRM2CHRM3CHRM4CHRM5SLC6A2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | APOBEC3A | P31941 | 2/20 | 0.43 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.43 |
| ▸ | GFER | P55789 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 4/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | INSR | P06213 | 1/20 | 0.37 |
| ▸ | CHAT | P28329 | 3/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8740741 | 0.88 | RELA (0.44) | MEN1KMT2ARAB9ANPC1APOBEC3A | |
| SCHEMBL8740701 | 0.83 | MEN1 (0.56) | MEN1KMT2ARAB9ANPC1APOBEC3A | |
| SCHEMBL8740680 | 0.82 | PPARG (0.40) | MEN1KMT2ANPC1ALDH1A1HTT | |
| SCHEMBL11386724 | 0.82 | RAB9A (0.51) | MEN1KMT2ARAB9ANPC1APOBEC3A | |
| SCHEMBL11386719 | 0.82 | RAB9A (0.51) | MEN1KMT2ARAB9ANPC1APOBEC3A | |
| SCHEMBL7178000 | 0.81 | HTT (0.42) | MEN1KMT2ARAB9ANPC1APOBEC3A | |
| SCHEMBL372527 | 0.79 | CHAT (0.61) | MEN1KMT2ARAB9ANPC1APOBEC3A | |
| SCHEMBL531127 | 0.77 | MEN1 (0.63) | MEN1KMT2ARAB9ANPC1APOBEC3A | |
| SCHEMBL531126 | 0.77 | MEN1 (0.63) | MEN1KMT2ARAB9ANPC1APOBEC3A | |
| SCHEMBL11384770 | 0.74 | RAB9A (0.51) | MEN1KMT2ARAB9ANPC1APOBEC3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6563622-B2 | High-speed communications system | TERABIT COMMUNICATIONS, L.L.C. | 2003-05-13 | — | — | US | claimed |
| CN-101377465-B | Inspection apparatus and inspection method using terahertz waves | CANON KK | 2011-11-09 | — | — | CN | disclosed |
| US-7963168-B2 | Inspection apparatus and inspection method using electromagnetic wave | CANON KABUSHIKI KAISHA (JP) | 2011-06-21 | — | — | US | disclosed |
| US-20090056455-A1 | INSPECTION APPARATUS AND INSPECTION METHOD USING ELECTROMAGNETIC WAVE | CANON KABUSHIKI KAISHA (JP) | 2009-03-05 | — | — | US | disclosed |
| EP-2031375-A2 | Inspection apparatus and inspection method using terahertz waves | Canon Kabushiki Kaisha (JP) | 2009-03-04 | — | — | EP | disclosed |
| CN-101377465-A | Inspection apparatus and inspection method using terahertz waves | CANON KK (JP) | 2009-03-04 | — | — | CN | disclosed |
| US-7387913-B2 | 3D optoelectronic micro system | JSR CORPORATION (JP) | 2008-06-17 | — | — | US | disclosed |
| US-20060261432-A1 | 3D optoelectronic micro system | JSR CORPORATION (JP) | 2006-11-23 | — | — | US | disclosed |
| US-20040247236-A1 | Three-Dimensional opto-electronic micro-system | YOSHIMURA, TETSUZO (JP) | 2004-12-09 | — | — | US | disclosed |