Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 8/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 7/20 | 0.35 |
| ▸ | S100A4 | P26447 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.31 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2488705 | 0.75 | HCRTR1 (0.41) | HCRTR2HCRTR1S100A4 | |
| SCHEMBL16031447 | 0.75 | HCRTR2 (0.44) | BRD4ADORA2AHCRTR2HCRTR1PIN1 | |
| SCHEMBL29912137 | 0.73 | S100A4 (0.38) | BRD4HCRTR2HCRTR1S100A4NPC1 | |
| SCHEMBL9955665 | 0.73 | S100A4 (0.38) | BRD4HCRTR2HCRTR1S100A4NPC1 | |
| SCHEMBL2495796 | 0.73 | PDE4B (0.38) | S100A4 | |
| SCHEMBL607939 | 0.73 | OPRK1 (0.43) | HCRTR2HCRTR1S100A4NPC1RAB9A | |
| SCHEMBL20135908 | 0.72 | OPRK1 (0.37) | BRD4HCRTR2HCRTR1PIN1HPGDS | |
| SCHEMBL16030471 | 0.72 | CFTR (0.45) | BRD4ADORA2AHCRTR2HCRTR1HPGD | |
| SCHEMBL609352 | 0.71 | APOBEC3A (0.32) | HCRTR2HCRTR1S100A4NPC1RAB9A | |
| SCHEMBL15984819 | 0.70 | LTA4H (0.44) | BRD4ADORA2ANPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970207-B1 | SUBSTITUTED PIPERIDINE COMPOUNDS AND THEIR USE AS OREXIN RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2018-05-16 | — | — | EP | claimed |