Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 4/20 | 0.40 |
| ▸ | CYSLTR1 | Q9Y271 | 4/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | BID | P55957 | 3/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.35 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.35 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.35 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | EP300 | Q09472 | 1/20 | 0.35 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.35 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.35 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.35 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.35 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.35 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8976650 | 0.74 | LMNA (0.38) | S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL8725831 | 0.73 | CYSLTR2 (0.43) | CYSLTR2CYSLTR1CASP1CASP7BID | |
| Bicarbonate SCHEMBL27586024 | 0.73 | LIPG (0.52) | CYSLTR2CYSLTR1BIDMCL1BCL2L1 | |
| SCHEMBL9189040 | 0.73 | CYSLTR2 (0.44) | CYSLTR2CYSLTR1BIDMCL1BCL2L1 | |
| SCHEMBL8729803 | 0.72 | CASP1 (0.37) | CYSLTR2CYSLTR1CASP1CASP7S1PR1 | |
| SCHEMBL8736020 | 0.71 | S1PR5 (0.36) | PPARGPPARAS1PR1S1PR3S1PR4 | |
| SCHEMBL7513588 | 0.71 | CASP1 (0.41) | CYSLTR2CYSLTR1CASP1CASP7S1PR5 | |
| SCHEMBL16166734 | 0.70 | POLB (0.45) | S1PR1S1PR5POLB | |
| SCHEMBL10787898 | 0.70 | HDAC4 (0.38) | CYSLTR2CYSLTR1CASP1CASP7S1PR1 | |
| SCHEMBL28226552 | 0.70 | CYP2C19 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2547646-B1 | HIGH SOLVATING CYCLOHEXANE DICARBOXYLATE DIESTERS PLASTICIZERS | EASTMAN CHEM CO (US) | 2018-05-16 | — | — | EP | claimed |