SCHEMBL7513588

SCHEMBL7513588

CCCCC1(c2ccccc2CC)CCC(C(=O)O)CC1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CASP1 P29466 1/20 0.41
CASP7 P55210 1/20 0.41
HDAC4 P56524 1/20 0.41
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
POLB P06746 1/20 0.38
CYSLTR2 Q9NS75 2/20 0.34
CYSLTR1 Q9Y271 2/20 0.34
ABL1 P00519 1/20 0.34
RIN1 Q13671 1/20 0.34
KCNH2 Q12809 1/20 0.34
OPRM1 P35372 3/20 0.34
OPRD1 P41143 3/20 0.34
OPRK1 P41145 3/20 0.34
OPRL1 P41146 3/20 0.34
CES2 O00748 1/20 0.34
CES1 P23141 1/20 0.34
ALDH1A1 P00352 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
S1PR5 Q9H228 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8729803 0.92 CASP1 (0.37) CASP1CASP7HDAC4MEN1KMT2A
SCHEMBL8725831 0.89 CYSLTR2 (0.43) CASP1CASP7CYSLTR2CYSLTR1S1PR5
SCHEMBL9189040 0.88 CYSLTR2 (0.44) CYSLTR2CYSLTR1S1PR5
SCHEMBL8562488 0.86 HSD11B1 (0.39) HDAC4MEN1KMT2APOLBABL1
SCHEMBL8043547 0.83 L3MBTL1 (0.40) MEN1KMT2APOLBS1PR5L3MBTL1
SCHEMBL11226164 0.83 TSHR (0.39) MEN1KMT2APOLBABL1RIN1
SCHEMBL7511121 0.82 HSD11B1 (0.39) HDAC4MEN1KMT2APOLBKCNH2
SCHEMBL7507861 0.81 S1PR1 (0.38) HDAC4MEN1KMT2APOLBCYSLTR2
SCHEMBL3358667 0.80 MEN1 (0.35) MEN1KMT2APOLBCYSLTR2CYSLTR1
SCHEMBL7514436 0.80 HTT (0.43) MEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0742275-B1 LIQUID CRYSTAL COMPOUND AND LIQUID CRYSTAL COMPOSITION CONTAINING THE SAME CHISSO CORP (JP) 2002-03-20 EP disclosed
US-5779936-A FLUORINATED BICYCLOHEXANE OR CYCLOHEXYLETHYL CYCLOHEXANE DERIVATIVE HAVING LOW VISCOSITY AND HIGH CLEARING POINT TEMPERATURE CHISSO CORPORATION (JP) 1998-07-14 US disclosed
EP-0742275-A1 LIQUID CRYSTAL COMPOUND AND LIQUID CRYSTAL COMPOSITION CONTAINING THE SAME CHISSO CORPORATION (JP) 1996-11-13 EP disclosed