SCHEMBL2013658

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2013677	0.84	HPGD (0.43)	SMN1; SMN2LMNAMEN1KMT2AALDH1A1
	SCHEMBL2017386	0.84	HTR2C (0.47)	HTR6SMN1; SMN2HTR2AHTR2CHTR2B
	SCHEMBL2016267	0.83	HTR2C (0.43)	HTR6HTR2AHTR2CHTR2BALDH1A1
	SCHEMBL2015259	0.82	HTR6 (0.45)	HTR6SMN1; SMN2HTR2AHTR2CHTR2B
	SCHEMBL2014452	0.82	MAPT (0.45)	HTR6HTR2AHTR2CHTR2BLMNA
	SCHEMBL2015962	0.80	HTR2C (0.41)	HTR6HTR2AHTR2CHTR2BTDP1
	SCHEMBL2015014	0.80	SMN1; SMN2 (0.52)	HTR6SMN1; SMN2HTR2CHTR2BLMNA
	SCHEMBL2017184	0.80	BRD4 (0.45)	HTR6SMN1; SMN2HTR2AHTR2CHTR2B
	SCHEMBL2018437	0.80	HTR2C (0.41)	HTR6SMN1; SMN2HTR2AHTR2CHTR2B
	SCHEMBL2021459	0.79	HTR2C (0.40)	HTR6HTR2AHTR2CHTR2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.