SCHEMBL2015014

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2017386	0.90	HTR2C (0.47)	SMN1; SMN2LMNAKDM4EKMT2APKM
	SCHEMBL2017184	0.90	BRD4 (0.45)	SMN1; SMN2PKMHTR2CHTR6HTR2B
	SCHEMBL2015259	0.90	HTR6 (0.45)	SMN1; SMN2LMNAKDM4EKMT2AHTR2C
	SCHEMBL2014308	0.90	HTR6 (0.49)	SMN1; SMN2LMNAKDM4EKMT2APKM
	SCHEMBL2018298	0.89	BRD4 (0.48)	SMN1; SMN2LMNAKDM4EKMT2AHTR2C
	SCHEMBL2017668	0.88	BRD4 (0.48)	LMNAKMT2APKMHTR2CHTR6
	SCHEMBL2015962	0.86	HTR2C (0.41)	PKMHTR2CHTR6HTR2BBRD4
	SCHEMBL2016961	0.86	PKM (0.52)	SMN1; SMN2LMNAKMT2APKMHTR2C
	SCHEMBL2018437	0.86	HTR2C (0.41)	SMN1; SMN2LMNAKDM4EKMT2APKM
	SCHEMBL2015995	0.85	BRD4 (0.46)	KMT2APKMHTR2CHTR6BRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.