Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.45 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.45 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.43 |
| ▸ | PPARA | Q07869 | 2/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MGAM | O43451 | 1/20 | 0.40 |
| ▸ | SI | P14410 | 1/20 | 0.40 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.39 |
| ▸ | TUBB | P07437 | 1/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.39 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27281641 | 0.86 | DYRK1A (0.44) | DYRK1ATRPV1LOXL2AKR1B1PPARA | |
| SCHEMBL9320873 | 0.85 | RAB9A (0.49) | DYRK1AAKR1B1PPARANPC1RAB9A | |
| SCHEMBL9675635 | 0.84 | LOXL2 (0.47) | DYRK1ATRPV1LOXL2AKR1B1PPARA | |
| SCHEMBL2947099 | 0.84 | NPC1 (0.63) | DYRK1ATRPV1LOXL2AKR1B1PPARA | |
| SCHEMBL31003151 | 0.84 | NPC1 (0.63) | DYRK1ATRPV1LOXL2AKR1B1PPARA | |
| SCHEMBL3247063 | 0.84 | LOXL2 (0.65) | DYRK1ATRPV1LOXL2AKR1B1PPARA | |
| Iodide SCHEMBL31511840 | 0.82 | LOXL2 (0.63) | DYRK1ATRPV1LOXL2AKR1B1PPARA | |
| Hydrochloric Acid SCHEMBL29456890 | 0.82 | LOXL2 (0.63) | DYRK1ATRPV1LOXL2AKR1B1PPARA | |
| Hydrochloric Acid SCHEMBL20511957 | 0.82 | LOXL2 (0.63) | DYRK1ATRPV1LOXL2AKR1B1PPARA | |
| SCHEMBL5946247 | 0.81 | DYRK1A (0.47) | DYRK1ATRPV1LOXL2AKR1B1PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250179008-A1 | ANTIBACTERIAL AGENTS | TAXIS PHARMACEUTICALS, INC. (US) | 2025-06-05 | — | — | US | disclosed |
| US-9428528-B2 | Phenicol antibacterials | ZOETIS SERVICES LLC (US) | 2016-08-30 | — | — | US | disclosed |
| US-9428528-B2 | Phenicol antibacterials | ZOETIS SERVICES LLC (US) | 2016-08-30 | — | — | US | disclosed |
| US-9428528-B2 | Phenicol antibacterials | ZOETIS SERVICES LLC (US) | 2016-08-30 | — | — | US | disclosed |
| US-20160194342-A1 | PHENICOL ANTIBACTERIALS | ZOETIS SERVICES LLC (US) | 2016-07-07 | — | — | US | disclosed |
| US-20160194342-A1 | PHENICOL ANTIBACTERIALS | ZOETIS SERVICES LLC (US) | 2016-07-07 | — | — | US | disclosed |
| US-20160194342-A1 | PHENICOL ANTIBACTERIALS | ZOETIS SERVICES LLC (US) | 2016-07-07 | — | — | US | disclosed |
| US-9340564-B2 | Phenicol antibacterials | ZOETIS SERVICES LLC (US) | 2016-05-17 | — | — | US | disclosed |
| US-9340564-B2 | Phenicol antibacterials | ZOETIS SERVICES LLC (US) | 2016-05-17 | — | — | US | disclosed |
| US-9340564-B2 | Phenicol antibacterials | ZOETIS SERVICES LLC (US) | 2016-05-17 | — | — | US | disclosed |
| WO-2007107758-A1 | ANTIBACTERIAL AGENTS | PROLYSIS LTD (GB) | 2007-09-27 | — | — | WO | disclosed |
| WO-2007107758-A1 | ANTIBACTERIAL AGENTS | PROLYSIS LTD (GB) | 2007-09-27 | — | — | WO | disclosed |
| US-5330997-A | 1H-indazole-3-acetic acids as aldose reductase inhibitors | PFIZER INC. (US) | 1994-07-19 | — | — | US | disclosed |
| US-5236945-A | 1H-indazole-3-acetic acids as aldose reductase inhibitors | PFIZER INC. (US) | 1993-08-17 | — | — | US | disclosed |
| EP-0325375-B1 | 1H-INDAZOLE-3-ACETIC ACIDS AS ALDOSE REDUCTASE INHIBITORS | PFIZER INC. (US) | 1992-08-12 | — | — | EP | disclosed |
| EP-0222576-B1 | HETEROCYCLIC OXOPHTHALAZINYL ACETIC ACIDS | PFIZER INC. (US) | 1992-03-18 | — | — | EP | disclosed |
| US-4939140-A | ALDOSE REDUCTASE INHIBITORS | PFIZER INC. (US) | 1990-07-03 | — | — | US | disclosed |
| WO-1989006651-A1 | 1H-INDAZOLE-3-ACETIC ACIDS AS ALDOSE REDUCTASE INHIBITORS | PFIZER INC. (US) | 1989-07-27 | — | — | WO | disclosed |
| EP-0325375-A1 | 1H-indazole-3-acetic acids as aldose reductase inhibitors | PFIZER INC. (US) | 1989-07-26 | — | — | EP | disclosed |
| EP-0222576-A2 | Heterocyclic oxophthalazinyl acetic acids | PFIZER INC. (US) | 1987-05-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160194342-A1 | PHENICOL ANTIBACTERIALS | MRPL21, TTL, CTSL | DYRK1A 2301/4885TRPV1 1655/4885LOXL2 38/4885 |
| US-20250179008-A1 | ANTIBACTERIAL AGENTS | ALK, ROS1, NOX1 | DYRK1A 4146/4885TRPV1 3827/4885LOXL2 1520/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.