Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL356920 | 0.87 | BACE1 (0.39) | BACE1 | |
| SCHEMBL29002023 | 0.78 | GAA (0.37) | — | |
| SCHEMBL20165 | 0.78 | DHFR (0.33) | — | |
| SCHEMBL156784 | 0.78 | ATAD2 (0.48) | ATAD2 | |
| SCHEMBL5491579 | 0.77 | TLR8 (0.44) | — | |
| SCHEMBL161148 | 0.76 | ATAD2 (0.54) | ATAD2 | |
| SCHEMBL356158 | 0.76 | TLR8 (0.45) | — | |
| SCHEMBL542389 | 0.71 | PNP (0.37) | — | |
| SCHEMBL2938692 | 0.70 | PNP (0.31) | — | |
| Thymine SCHEMBL219100 | 0.70 | ATAD2 (0.63) | ATAD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10633410-B2 | Nucleic acid aptamers to treat histone-induced disease states | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2020-04-28 | — | — | US | disclosed |
| US-20180134746-A1 | NUCLEIC ACID APTAMERS TO TREAT HISTONE-INDUCED DISEASE STATES | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2018-05-17 | — | — | US | disclosed |