SCHEMBL2013845

SCHEMBL2013845

Fc1cc(F)cc(-c2cc[c]cc2C(F)(F)F)c1

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
AR P10275 1/20 0.32
TRPA1 O75762 1/20 0.31
KIF11 P52732 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2426849 0.85 CYP11B2 (0.42) ARTRPA1
SCHEMBL2433534 0.84 PDE3B (0.36) ARTRPA1KIF11
SCHEMBL3021267 0.82 RXRA (0.35) AR
SCHEMBL17514477 0.81 AR (0.30) AR
SCHEMBL14483362 0.80 GLA (0.38)
SCHEMBL2431534 0.79 PDE3B (0.40) ARTRPA1KIF11
SCHEMBL1369645 0.78 KIF11 (0.38) ARKIF11
SCHEMBL17514793 0.77 AKR1C3 (0.45) AR
SCHEMBL3636363 0.76 KIF11 (0.41) ARKIF11
SCHEMBL2053792 0.76 PDE3B (0.38) ARTRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013182433-A1 A PROCESS USING GRIGNARD REAGENTS BASF SE (DE) 2013-12-12 WO disclosed
EP-2547687-A1 A PROCESS USING GRIGNARD REAGENTS BASF SE (DE) 2013-01-23 EP disclosed
EP-2513067-A1 METHOD FOR PRODUCING TRIAZOLINTHIONE DERIVATIVES AND INTERMEDIATES THEREOF BASF SE (DE) 2012-10-24 EP disclosed
WO-2011113820-A1 A PROCESS USING GRIGNARD REAGENTS BASF SE (DE) 2011-09-22 WO disclosed
WO-2011073145-A1 METHOD FOR PRODUCING TRIAZOLINTHIONE DERIVATIVES AND INTERMEDIATES THEREOF BASF SE (DE) 2011-06-23 WO disclosed