Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.38 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | GGT1 | P19440 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CFD | P00746 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1451808 | 0.82 | KDM4E (0.44) | KDM4ETSHRALDH1A1HSD17B10ESR1 | |
| SCHEMBL20262200 | 0.79 | ACHE (0.42) | KDM4ETSHRALDH1A1HSD17B10ESR1 | |
| SCHEMBL4998918 | 0.78 | CYP4F2 (0.44) | KDM4ETSHRALDH1A1HSD17B10ESR1 | |
| SCHEMBL3197508 | 0.78 | TSHR (0.49) | KDM4ETSHRALDH1A1HSD17B10ESR1 | |
| SCHEMBL1205065 | 0.78 | TNFSF11 (0.46) | KDM4ETSHRALDH1A1HSD17B10ESR1 | |
| SCHEMBL8040089 | 0.78 | CFD (0.40) | KDM4ETSHRALDH1A1HSD17B10ESR1 | |
| SCHEMBL6962146 | 0.78 | KDM4E (0.40) | KDM4ETSHRALDH1A1HSD17B10ESR1 | |
| SCHEMBL6200251 | 0.76 | KDM4E (0.58) | KDM4ETSHRALDH1A1HSD17B10ESR1 | |
| SCHEMBL20138635 | 0.76 | SMN1; SMN2 (0.41) | KDM4ETSHRALDH1A1HSD17B10ESR1 | |
| SCHEMBL226719 | 0.75 | NR1H4 (0.39) | KDM4ETSHRALDH1A1HSD17B10ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3538080-A1 | CONJUGATION LINKERS, CELL BINDING MOLECULE-DRUG CONJUGATES CONTAINING THE LIKERS, METHODS OF MAKING AND USES SUCH CONJUGATES WITH THE LINKERS | Hangzhou Dac Biotech Co. Ltd. (CN) | 2019-09-18 | — | — | EP | disclosed |
| WO-2018086139-A1 | CONJUGATION LINKERS, CELL BINDING MOLECULE-DRUG CONJUGATES CONTAINING THE LIKERS, METHODS OF MAKING AND USES SUCH CONJUGATES WITH THE LINKERS | HANGZHOU DAC BIOTECH CO., LTD (CN) | 2018-05-17 | — | — | WO | disclosed |