SCHEMBL226719

SCHEMBL226719

CC(=O)Oc1cc[c]cc1C(C)(C)C

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR1H4 Q96RI1 1/20 0.39
TDP1 Q9NUW8 2/20 0.36
ATM Q13315 1/20 0.36
KDM4E B2RXH2 5/20 0.36
ALDH1A1 P00352 3/20 0.36
TSHR P16473 3/20 0.36
HSD17B10 Q99714 3/20 0.36
HPGD P15428 2/20 0.36
ESR1 P03372 1/20 0.36
ITGB3 P05106 1/20 0.36
ITGA2B P08514 1/20 0.36
HMGB1 P09429 1/20 0.36
GGT1 P19440 1/20 0.36
PTGS1 P23219 1/20 0.36
PTGS2 P35354 1/20 0.36
BLM P54132 1/20 0.36
NAPRT Q6XQN6 1/20 0.36
GAA P10253 1/20 0.35
RAB9A P51151 1/20 0.35
CFD P00746 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1451808 0.80 KDM4E (0.44) TDP1KDM4EALDH1A1TSHRHSD17B10
SCHEMBL23212522 0.79 ACE (0.32) TDP1ATMKDM4EALDH1A1
SCHEMBL20262200 0.77 ACHE (0.42) TDP1KDM4EALDH1A1TSHRHSD17B10
SCHEMBL996826 0.76 LMNA (0.38) ALDH1A1HPGDGAALMNACYP3A4
SCHEMBL20138650 0.75 KDM4E (0.38) TDP1KDM4EALDH1A1TSHRHSD17B10
SCHEMBL4998918 0.75 CYP4F2 (0.44) TDP1KDM4EALDH1A1TSHRHSD17B10
SCHEMBL3197508 0.75 TSHR (0.49) TDP1KDM4EALDH1A1TSHRHSD17B10
SCHEMBL1205065 0.75 TNFSF11 (0.46) TDP1KDM4EALDH1A1TSHRHSD17B10
SCHEMBL6962146 0.75 KDM4E (0.40) TDP1KDM4EALDH1A1TSHRHSD17B10
SCHEMBL8040089 0.75 CFD (0.40) TDP1KDM4EALDH1A1TSHRHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7323511-B2 Post-coupling synthetic approach for polymeric antioxidants UNIVERSITY OF MASSACHUSETTS LOWELL (US) 2008-01-29 US claimed
EP-1846460-A2 POST-COUPLING SYNTHETIC APPROACH FOR POLYMERIC ANTIOXIDANTS UNIVERSITY OF MASSACHUSETTS LOWELL (US) 2007-10-24 EP claimed
US-20050238789-A1 Post-coupling synthetic approach for polymeric antioxidants UNIVERSITY OF MASSACHUSETTS LOWELL (US) 2005-10-27 US claimed
WO-2005070974-A2 POST-COUPLING SYNTHETIC APPROACH FOR POLYMERIC ANTIOXIDANTS UNIVERSITY OF MASSACHUSETTS LOWELL (US) 2005-08-04 WO claimed
US-9523060-B2 Lubricant oil compositions POLNOX CORPORATION (US) 2016-12-20 US disclosed
US-20150159109-A1 Lubricant Oil Compositions POLNOX CORPORATION 2015-06-11 US disclosed
US-8927472-B2 Lubricant oil compositions POLNOX CORPORATION (US) 2015-01-06 US disclosed
US-20140011901-A1 Stabilized Polyolefin Compositions POLNOX CORPORATION (US) 2014-01-09 US disclosed
US-8481670-B2 Stabilized polyolefin compositions POLNOX CORPORATION (US) 2013-07-09 US disclosed
US-20130130955-A1 LUBRICANT OIL COMPOSITIONS POLNOX CORPORATION (US) 2013-05-23 US disclosed
US-20130072586-A1 Stabilized Polyolefin Compositions POLNOX CORPORATION (US) 2013-03-21 US disclosed
US-8252884-B2 Stabilized polyolefin compositions POLNOX CORPORATION (US) 2012-08-28 US disclosed
US-7705075-B2 Stabilized polyolefin compositions POLNOX CORPORATION (US) 2010-04-27 US disclosed
US-20080293856-A1 Stabilized polyolefin compositions POLNOX CORPORATION 2008-11-27 US disclosed
US-7323511-B2 Post-coupling synthetic approach for polymeric antioxidants UNIVERSITY OF MASSACHUSETTS LOWELL (US) 2008-01-29 US disclosed
EP-1846460-A2 POST-COUPLING SYNTHETIC APPROACH FOR POLYMERIC ANTIOXIDANTS UNIVERSITY OF MASSACHUSETTS LOWELL (US) 2007-10-24 EP disclosed
US-20070161522-A1 Lubricant oil compositions POLNOX CORPORATION 2007-07-12 US disclosed
US-20070149660-A1 Stabilized polyolefin compositions POLNOX CORPORATION 2007-06-28 US disclosed
US-20050238789-A1 Post-coupling synthetic approach for polymeric antioxidants UNIVERSITY OF MASSACHUSETTS LOWELL (US) 2005-10-27 US disclosed
WO-2005070974-A2 POST-COUPLING SYNTHETIC APPROACH FOR POLYMERIC ANTIOXIDANTS UNIVERSITY OF MASSACHUSETTS LOWELL (US) 2005-08-04 WO disclosed