Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.40 |
| ▸ | FABP3 | P05413 | 1/20 | 0.39 |
| ▸ | FABP4 | P15090 | 1/20 | 0.39 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | DHODH | Q02127 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | EIF4A1 | P60842 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | PRNP | P04156 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28027214 | 0.86 | P2RX3 (0.42) | PDE10AALDH1A1KDM4EL3MBTL1P2RX3 | |
| SCHEMBL18420435 | 0.76 | ALOX5 (0.47) | ALDH1A1KDM4EGAAMAPTMEN1 | |
| SCHEMBL2821238 | 0.76 | FABP4 (0.46) | ALDH1A1KDM4EL3MBTL1FABP3FABP4 | |
| SCHEMBL22734576 | 0.72 | P2RX3 (0.45) | PDE10AALDH1A1KDM4EP2RX3GAA | |
| SCHEMBL8874588 | 0.71 | FABP3 (0.43) | PDE10AALDH1A1KDM4EL3MBTL1FABP3 | |
| SCHEMBL3061423 | 0.70 | DHODH (0.50) | P2RX3FABP3FABP4FABP5KMT2A | |
| SCHEMBL6080337 | 0.70 | CDK9 (0.41) | PDE10AALDH1A1KDM4EP2RX3GAA | |
| SCHEMBL3234894 | 0.69 | KDM4E (0.68) | PDE10AALDH1A1KDM4EL3MBTL1GAA | |
| SCHEMBL6588228 | 0.68 | MAPT (0.49) | PDE10AALDH1A1KDM4EL3MBTL1GAA | |
| SCHEMBL3066041 | 0.68 | DHODH (0.47) | ALDH1A1P2RX3FABP3FABP4FABP5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11505545-B2 | Anthelmintic quinoline-3-carboxamide derivatives | BAYER ANIMAL HEALTH GMBH (DE) | 2022-11-22 | — | — | US | disclosed |
| EP-3538512-B1 | NEW ANTHELMINTIC QUINOLINE-3-CARBOXAMIDE DERIVATIVES | BAYER ANIMAL HEALTH GMBH (DE) | 2021-06-16 | — | — | EP | disclosed |
| US-20210115026-A1 | NEW ANTHELMINTIC QUINOLINE-3-CARBOXAMIDE DERIVATIVES | ELANCO ANIMAL HEALTH GMBH (DE) | 2021-04-22 | — | — | US | disclosed |
| US-10889573-B2 | Anthelmintic quinoline-3-carboxamide derivatives | BAYER ANIMAL HEALTH GMBH (DE) | 2021-01-12 | — | — | US | disclosed |
| EP-3538512-A1 | NEW ANTHELMINTIC QUINOLINE-3-CARBOXAMIDE DERIVATIVES | Bayer Animal Health GmbH (DE) | 2019-09-18 | — | — | EP | disclosed |
| WO-2018087036-A1 | NEW ANTHELMINTIC QUINOLINE-3-CARBOXAMIDE DERIVATIVES | BAYER ANIMAL HEALTH GMBH (DE) | 2018-05-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11505545-B2 | Anthelmintic quinoline-3-carboxamide derivatives | HRH4, HRH2, H1-5 | PDE10A 2936/4885ALDH1A1 1655/4885KDM4E 973/4885 |
| US-20210115026-A1 | NEW ANTHELMINTIC QUINOLINE-3-CARBOXAMIDE DERIVATIVES | HRH4, HRH2, HRH1 | PDE10A 2657/4885ALDH1A1 1833/4885KDM4E 981/4885 |
| US-10889573-B2 | Anthelmintic quinoline-3-carboxamide derivatives | HRH4, HRH2, H1-5 | PDE10A 2976/4885ALDH1A1 1646/4885KDM4E 947/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.