Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | GRM5 | P41594 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 3/20 | 0.47 |
| ▸ | HTR7 | P34969 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20139683 | 0.81 | KMT2A (0.51) | POLBTHRBMEN1KMT2AALDH1A1 | |
| SCHEMBL20140717 | 0.76 | KMT2A (0.49) | POLBTHRBMEN1KMT2AALDH1A1 | |
| SCHEMBL20159302 | 0.74 | TP53 (0.53) | POLBMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL20159024 | 0.70 | MTOR (0.64) | POLBMEN1KMT2AHTR1AHTR7 | |
| SCHEMBL16501806 | 0.69 | MEN1 (0.78) | MEN1KMT2AGRM5HTR1AHTR7 | |
| SCHEMBL6263437 | 0.68 | ALDH1A1 (0.64) | POLBMEN1KMT2AHTR1AHTR7 | |
| SCHEMBL5763767 | 0.68 | ALDH1A1 (0.57) | MEN1KMT2AHTR1AHTR7ALDH1A1 | |
| SCHEMBL6495850 | 0.67 | ALDH1A1 (0.66) | MEN1KMT2AHTR1AHTR7ALDH1A1 | |
| SCHEMBL5751986 | 0.67 | MEN1 (0.61) | MEN1KMT2AHTR1AHTR7ALDH1A1 | |
| SCHEMBL9320601 | 0.66 | MEN1 (0.68) | MEN1KMT2AGRM5HTR1AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089493-A1 | PYRROLE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |