Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.51 |
| ▸ | MEN1 | O00255 | 6/20 | 0.51 |
| ▸ | TSHR | P16473 | 5/20 | 0.51 |
| ▸ | USP2 | O75604 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.50 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.49 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.49 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20140717 | 0.83 | KMT2A (0.49) | KMT2AMEN1TSHRUSP2ALDH1A1 | |
| SCHEMBL20139281 | 0.81 | POLB (0.52) | KMT2AMEN1TSHRUSP2ALDH1A1 | |
| SCHEMBL20159302 | 0.80 | TP53 (0.53) | KMT2AMEN1TSHRUSP2ALDH1A1 | |
| SCHEMBL3383184 | 0.77 | HRH3 (0.57) | — | |
| SCHEMBL20142393 | 0.77 | MEN1 (0.56) | KMT2AMEN1TSHRUSP2ALDH1A1 | |
| SCHEMBL24610019 | 0.77 | TSHR (0.66) | KMT2AMEN1TSHRUSP2ALDH1A1 | |
| SCHEMBL30125105 | 0.75 | CYP1A2 (0.58) | KMT2AMEN1TSHRUSP2ALDH1A1 | |
| SCHEMBL5658689 | 0.75 | USP2 (0.78) | KMT2AMEN1TSHRUSP2ALDH1A1 | |
| SCHEMBL9268443 | 0.72 | HDAC10 (0.66) | KMT2AMEN1ALDH1A1POLB | |
| SCHEMBL16403979 | 0.72 | MGLL (0.48) | KMT2AMEN1TSHRUSP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089493-A1 | PYRROLE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |
| WO-2018089493-A1 | PYRROLE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |