Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | POLB | P06746 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | MTOR | P42345 | 1/20 | 0.47 |
| ▸ | RPTOR | Q8N122 | 1/20 | 0.47 |
| ▸ | MLST8 | Q9BVC4 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | USP2 | O75604 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.43 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.43 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20139683 | 0.83 | KMT2A (0.51) | KMT2APOLBMEN1THRBALDH1A1 | |
| SCHEMBL20139281 | 0.76 | POLB (0.52) | KMT2APOLBMEN1THRBALDH1A1 | |
| SCHEMBL20159024 | 0.74 | MTOR (0.64) | KMT2APOLBMEN1MTORRPTOR | |
| SCHEMBL20159302 | 0.73 | TP53 (0.53) | KMT2APOLBMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL20139786 | 0.73 | MTOR (0.51) | KMT2APOLBMEN1THRBMTOR | |
| SCHEMBL20139225 | 0.70 | MTOR (0.50) | KMT2AMTORRPTORMLST8 | |
| SCHEMBL5658689 | 0.69 | USP2 (0.78) | KMT2AMEN1ALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL20142393 | 0.69 | MEN1 (0.56) | KMT2APOLBMEN1THRBALDH1A1 | |
| SCHEMBL20140555 | 0.67 | MTOR (0.78) | KMT2APOLBMEN1MTORRPTOR | |
| SCHEMBL20159115 | 0.67 | MTOR (0.55) | POLBMTORRPTORMLST8SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089493-A1 | PYRROLE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |