Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.32 |
| ▸ | UNG | P13051 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.31 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20139218 | 0.82 | ALDH1A1 (0.38) | HDAC8ALDH1A1 | |
| SCHEMBL16372656 | 0.81 | GPR35 (0.36) | HDAC8UNGALDH1A1TRIM24TRIM33 | |
| SCHEMBL10428341 | 0.74 | PADI4 (0.32) | HDAC8UNGALDH1A1TRIM24TRIM33 | |
| SCHEMBL1441399 | 0.68 | HDAC8 (0.47) | HDAC8UNGALDH1A1TRIM24TRIM33 | |
| SCHEMBL30838222 | 0.67 | PTGDR2 (0.32) | — | |
| SCHEMBL23354136 | 0.65 | ALDH1A1 (0.37) | ALDH1A1 | |
| SCHEMBL31286442 | 0.63 | KDM4E (0.35) | ALDH1A1 | |
| SCHEMBL30322877 | 0.61 | KDM4C (0.34) | ALDH1A1PTGS2 | |
| SCHEMBL27362223 | 0.61 | PTGDR2 (0.30) | — | |
| SCHEMBL30838224 | 0.60 | CNR1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089493-A1 | PYRROLE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |
| WO-2018089493-A1 | PYRROLE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |