Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | RPTOR | Q8N122 | 1/20 | 0.40 |
| ▸ | MLST8 | Q9BVC4 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | SMO | Q99835 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | NAAA | Q02083 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20139330 | 1.00 | FAAH (0.44) | FAAHPTGDR2MTORRPTORMLST8 | |
| SCHEMBL20139783 | 0.89 | SCD5 (0.44) | FAAHPTGDR2MTORRPTORMLST8 | |
| SCHEMBL20140557 | 0.89 | SCD5 (0.44) | FAAHPTGDR2MTORRPTORMLST8 | |
| SCHEMBL20139784 | 0.89 | SCD5 (0.44) | FAAHPTGDR2MTORRPTORMLST8 | |
| SCHEMBL20159012 | 0.74 | MTOR (0.72) | PTGDR2MTORRPTORMLST8CHRM4 | |
| SCHEMBL17324966 | 0.74 | FAAH (0.53) | FAAHPTGDR2CHRM4SMOMAPK1 | |
| SCHEMBL9959713 | 0.74 | NOTUM (0.54) | FAAHPTGDR2CHRM4SMOMAPK1 | |
| SCHEMBL20159285 | 0.73 | MTOR (0.51) | FAAHPTGDR2MTORRPTORMLST8 | |
| SCHEMBL20158920 | 0.73 | MTOR (0.51) | FAAHPTGDR2MTORRPTORMLST8 | |
| SCHEMBL20140654 | 0.72 | MTOR (0.68) | PTGDR2MTORRPTORMLST8CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089493-A1 | PYRROLE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |