Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | RPTOR | Q8N122 | 1/20 | 0.41 |
| ▸ | MLST8 | Q9BVC4 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 2/20 | 0.40 |
| ▸ | CTSS | P25774 | 2/20 | 0.40 |
| ▸ | CTSK | P43235 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | SMO | Q99835 | 3/20 | 0.39 |
| ▸ | KRAS | P01116 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20139784 | 1.00 | SCD5 (0.44) | SCD5FAAHNPC1RAB9AAGTR2 | |
| SCHEMBL20139783 | 1.00 | SCD5 (0.44) | SCD5FAAHNPC1RAB9AAGTR2 | |
| SCHEMBL20139330 | 0.89 | FAAH (0.44) | FAAHNPC1RAB9AKMT2AMTOR | |
| SCHEMBL20139331 | 0.89 | FAAH (0.44) | FAAHNPC1RAB9AKMT2AMTOR | |
| SCHEMBL20142393 | 0.81 | MEN1 (0.56) | KMT2AMEN1MAPTPOLBCTDSP1 | |
| SCHEMBL20140327 | 0.80 | SCD5 (0.44) | SCD5FAAHNPC1RAB9AAGTR2 | |
| SCHEMBL20140329 | 0.80 | SCD5 (0.44) | SCD5FAAHNPC1RAB9AAGTR2 | |
| SCHEMBL20159042 | 0.78 | DRD2 (0.42) | NPC1RAB9AKMT2ACTSBCTSS | |
| SCHEMBL20139213 | 0.73 | FAAH (0.54) | SCD5FAAHNPC1RAB9AAGTR2 | |
| SCHEMBL27606539 | 0.73 | FAAH (0.54) | SCD5FAAHNPC1RAB9AAGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089493-A1 | PYRROLE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |
| WO-2018089493-A1 | PYRROLE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |