Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.40 |
| ▸ | KHK | P50053 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 3/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | BCL2A1 | Q16548 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20157447 | 0.88 | MAPT (0.45) | MAPTHRH4KHKSLC6A2SLC6A4 | |
| SCHEMBL20157184 | 0.79 | MAPT (0.46) | MAPTHRH4KHKHTR7BCL2A1 | |
| Trifluoroacetic Acid SCHEMBL20141711 | 0.76 | HTR2C (0.39) | HRH4 | |
| SCHEMBL20139839 | 0.72 | MAPT (0.38) | MAPTKHKHSD11B1BCL2A1 | |
| Trifluoroacetic Acid SCHEMBL23855508 | 0.70 | MAPT (0.47) | MAPT | |
| Trifluoroacetic Acid SCHEMBL23855507 | 0.70 | MAPT (0.47) | MAPT | |
| SCHEMBL4588673 | 0.70 | MAPT (0.47) | MAPTHRH4KHKHSD11B1BCL2A1 | |
| SCHEMBL4588676 | 0.70 | MAPT (0.47) | MAPTHRH4KHKHSD11B1BCL2A1 | |
| SCHEMBL20139337 | 0.70 | SUV39H2 (0.47) | CHRM1CHRM3CHRM5 | |
| SCHEMBL20139336 | 0.70 | SUV39H2 (0.47) | CHRM1CHRM3CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089493-A1 | PYRROLE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |