Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | KHK | P50053 | 2/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 3/20 | 0.40 |
| ▸ | BCL2A1 | Q16548 | 2/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.40 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.39 |
| ▸ | GABRP | O00591 | 1/20 | 0.38 |
| ▸ | GABRD | O14764 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20157184 | 0.90 | MAPT (0.46) | MAPTKHKHTR7BCL2A1HRH4 | |
| Trifluoroacetic Acid SCHEMBL20139838 | 0.88 | TRPV1 (0.41) | MAPTKHKSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL1537900 | 0.79 | HTR3E (0.57) | SLC6A2SLC6A4SLC6A3HTR7 | |
| SCHEMBL6840540 | 0.77 | KCNH2 (0.46) | KCNH2SLC6A2SLC6A4SLC6A3HTR7 | |
| SCHEMBL4588673 | 0.77 | MAPT (0.47) | MAPTKHKBCL2A1HRH4 | |
| SCHEMBL4588676 | 0.77 | MAPT (0.47) | MAPTKHKBCL2A1HRH4 | |
| SCHEMBL6811911 | 0.75 | MAPT (0.46) | MAPTKHKKCNH2SLC6A2SLC6A4 | |
| SCHEMBL3340549 | 0.75 | LTA4H (0.48) | MAPTSLC6A2SLC6A4SLC6A3HTR7 | |
| SCHEMBL2249343 | 0.74 | HTR1A (0.63) | MAPTKHKBCL2A1TLR9TLR8 | |
| SCHEMBL949366 | 0.74 | HTR3A (0.56) | MAPTHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089493-A1 | PYRROLE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |